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find Author "雷尚通" 3 results
  • Clinical Significance on Exposure of Recurrent Laryngeal Nerve in Thyroid Surgery Avoiding Recurrent Laryngeal Nerve Injury

    Objective To explore the clinical significance of exposure the recurrent laryngeal nerve(RLN) for preventing the RLN injury in thyroidectomy. Methods The data of 1 723 patients with thyroid diseases undergoing total or subtotal thyroidectomy from September 2006 to August 2011 were retrospectively reviewed. RLN were exposed in 914 cases, 1 203 RLNs were exposed(exposed group). RLN were unexposed in 809 cases, 1 013 sides were cut(unexposed group). To compare RLN injury rate after operation and recovery of vocal cord in 6 months after operation between the two groups. Results In exposed group, 11 cases had RLN injury, the rate of RLN lesion was 0.91%. In unexposed group, 21 cases had RLN injury, the rate of RLN lesion was 2.07%. The differences between the two groups had statistical significance(P<0.05). When six months after operation, 0 case and 13 cases in exposed group and unexposed group respectively occurred permanent RLN injury, the differences between the two groups had statistical significance(P<0.01). Conclusion Exposure of RLN in total and subtotal thyroidectomy can significant avoid RLN injury, especially RLN permanent injury.

    Release date:2016-09-08 10:36 Export PDF Favorites Scan
  • Diagnosis and Treatment of Small Intestinal Haemorrhage with Laparoscopy: Experience of 15 Patients

    目的 探讨腹腔镜对小肠大出血的诊断和治疗。方法 对15例怀疑小肠大出血的患者进行腹腔镜探查。结果 探查阳性率100%,其中小肠肿瘤7例,小肠憩室5例,小肠憩室并套叠1例,小肠血管畸形2例,均在腹腔镜辅助下行小肠部分切除或憩室切除术。结论 腹腔镜对小肠出血的诊断尤其是治疗方面有较高的价值。

    Release date:2016-08-28 04:08 Export PDF Favorites Scan
  • Effects of X-Ray Dose on Expressions of MicroRNA-221 and PTEN in Human Colorectal Carcinoma Cells

    Objective To investigate the effects of X-ray dose on the expressions of microRNA-221 (miR-221) and phosphatase and a tensin homolog deleted from chromosome10 (PTEN) in human colorectal carcinoma (CRC) cells. Methods Human CRC-derived cell line, Caco2, was cultured conventionally. The cells were divided into five groups and exposed to different doses of X-ray (0, 2, 4, 6, and 8 Gy) respectively. The total RNA and protein of the Caco2 cells were extracted after irradiation, and the miR-221 and PTEN mRNA expressions were detected by real-time RT-PCR.Moreover, the protein alteration of PTEN in Caco2 cells was detected by Western-blot analysis. Results The radiation dose of X-ray significantly affected the expressions of miR-221 and PTEN protein in human Caco2 cells in a dose-depen-dent manner. Moreover, the miR-221 expression level was up-regulated gradually with the increase of irradiation dose, on the contrary, the PTEN protein expression level was down-regulated gradually (P<0.01). Conclusion The radiation dose can affect the miR-221 and PTEN protein expression pattern in CRC cells.

    Release date:2016-09-08 10:24 Export PDF Favorites Scan
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