目的探讨成人风湿性心脏瓣膜病术前并发心室电风暴(恶性室性心动过速、心室颤动)行急诊手术的疗效及体会。 方法回顾性分析2004年10月至2014年10月我院成人心脏瓣膜入院后突发恶性室性心动过速、心室颤动的患者6例,其中男2例,女4例,年龄35.0~64.0岁,平均49.8岁。6例患者均为风湿性心脏瓣膜病,二尖瓣中重度狭窄并主动脉瓣及三尖瓣中重度关闭不全2例,二尖瓣中重度关闭不全并三尖瓣中重度关闭不全4例,恶性心律失常发作后立即予艾司洛尔等药物控制,病情基本稳定后急诊手术。其中,行双瓣膜置换+三尖瓣成形术2例,行二尖瓣置换+三尖瓣成形术4例。 结果无围术期患者死亡,术后无心功能显著恶化、无多脏器功能衰竭、无恶性室性心律失常。术后1~2周24 h动态心电图提示室性早搏大于1 000次的2例,室性早搏500~1 000次1例,小于500次的患者3例,短阵室性心动过速2次的患者2例,短阵室性心动过速3次的患者1例。所有6例患者均安全出院,随访6个月至10年,无患者死亡。 结论急诊外科手术联合β受体阻滞剂在治疗成人心脏瓣膜疾病术前突发的反复恶性室性心动过速、心室颤动安全有效。
Objective To compare the effect of monopolar and bipolar radiofrequency ablation in patients with atrial fibrillation and concomitant rheumatic heart disease. Methods The clinical data of 261 patients who underwent valve replacement and radiofrequency Maze Ⅲ procedure in Shanghai First People's Hospital from 2010 to 2015 were retrospectively analyzed. According to the radiofrequency ablation system, patients were assigned to a monopolar radiofrequency ablation group (n=209, 129 males, 80 females, aged 59.6±9.7 years) and a bipolar radiofrequency ablation group (n=52, 36 males, 16 females, aged 58.6±11.2 years). After procedures, clinical factors such as patients' basic information, perioperative complication and mortality, the elimination rate of atrial fibrillation were measured. Results There was no statistic difference in perioperative morbidity and mortality between two groups. The ablation time of the monopolar radiofrequency ablation group was longer than that of the bipolar group (29.7±3.3 minvs. 22.3±7.8 min,P=0.035). Postoperative diameter of left atrium was reduced in both groups. Compared with the monopolar radiofrequency ablation group, bipolar group had a better elimination rate of atrial fibrillation at three months and one year follow-up (82.0%vs. 66.3%,P=0.037; 80.0%vs. 59.6%,P=0.008). Conclusion Valve replacement combined with radiofrequency Maze Ⅲ procedure is safe and efficient. Compared with monopolar radiofrequency ablation, bipolar radiofrequency ablation has advantage on elimination rate of atrial fibrillation, ablation time and cardiopulmonary bypass time.