目的 探讨炎性乳腺癌的临床特点和治疗方法。 方法 对我院1989年2月至1997年11月期间诊治的17例炎性乳腺癌患者的临床资料进行回顾性分析。 结果 17例患者中8例行新辅助化疗+乳腺癌改良根治术+术后放疗及化疗患者的平均生存期为33.6个月，1、2、5年仍存活者分别为6例、5例和3例，行其他治疗的9例患者1、2、5年仍存活者分别为5例、3例和0例。 结论 新辅助化疗+乳腺癌改良根治术+术后放疗及化疗可提高患者生存率。
Objective To study effects of enteral immunonutrition and econutrition on intestinal mucosa barrier function in wounded rats. Methods Forty Wistar rats were randomly divided into four groups, with ten rats in each group 〔ie.control group, enteral nutrition (EN) group, enteral immunonutrition (EIN) group and enteral econutrition (EEN) group〕. After gastrostomy, rats in each group were treated with the isocaloric and isonitrogenous nutritional formulas for 7 days, respectively. The morphology of ileum membrane was studied, and the quantities of IgA+, CD3+, CD4+ and CD8+ cells (each HP) of ileum membrane were determined. Results The villus height, crypt depth, mucosal thickness (except EN group) and villus surface area of ileum were increased in EN, EIN and EEN group compared with control group (P＜0.05), but there was no significant difference among the former three groups (Pgt;0.05). The numbers of IgA+, CD3+, CD4+ and CD8+ cells were increased in EN, EIN and EEN group compared with control group (P＜0.05), and those numbers in EN group were lower than those in EIN and EEN group (P＜0.05). Conclusion EIN and EEN may improve intestine mechanical barrier function and promote restoration of small intestine mucous membrane barrier function in rats. EIN and EEN also improve intestine immune barrier function and strengthen its immune function.