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find Author "黄信生" 2 results
  • 冠心病合并室壁瘤及二尖瓣关闭不全的外科治疗

    摘要: 目的 总结冠心病合并室壁瘤和二尖瓣关闭不全的外科治疗经验及效果。 方法 回顾性分析78例冠心病合并室壁瘤和二尖瓣关闭不全患者的临床资料,其中男45例,女33例;年龄42~70岁,平均年龄55岁。室壁瘤位于心尖部44例,外侧壁14例,下壁20例; 二尖瓣中度关闭不全48例,重度关闭不全30例。手术在低温体外循环下施行,室壁瘤线性缝合术24例,心内膜环缩、三明治缝合术36例,心内膜环缩、左心室补片成形术18例,同期血栓清除术13例;二尖瓣成形术42例,二尖瓣置换术36例;移植旁路血管1~6支(2.5±1.5支)。 结果 围术期死亡5例,死于败血症1例,多器官功能衰竭2例,心力衰竭2例。术中停机困难5例。术后主要并发症:低心排血量综合征、恶性心律失常和多器官功能衰竭。左心室舒张期末内径(55.6±1.2 mm vs. 68.2±4.0 mm),射血分数(45%±23% vs.34%±14%),心功能分级(NYHA,1.82±0.26级 vs. 3.36±0.56级)与术前比较差异均有统计学意义(Plt;0.05)。随访69例,随访率94.52%,随访时间25±8个月。随访期间无远期死亡,无症状复发。心功能Ⅰ~Ⅱ级58例,Ⅲ级9例,Ⅳ级2例, 较术前明显改善(Plt;0.05)。 结论 根据病理生理特点选择对心腔、血管和瓣膜全面处理的手术方式,加强围术期管理,手术治疗冠心病合并室壁瘤及二尖瓣关闭不全的近、远期疗效满意。

    Release date:2016-08-30 06:01 Export PDF Favorites Scan
  • Midterm and Longterm Clinical Outcome Analysis of Bilateral Internal Mammary Artery Composited Y Grafts for Coronary Artery Bypass Grafting

    Objective To evaluate midterm and longterm clinical outcome of bilateral internal mammary artery composited Y grafts for coronary artery bypass grafting (CABG), analyze risk factors for late death ,and to improve surgical results. Methods Between January 2000 and May 2004, One hundred and sixtyfive patients underwent bilateral internal mammary artery grafts for CABG, The clinical data, postoperative complications and survival results were retrospectively reviewed and analyzed. The preoperative and postoperative cardiac function was compared. All factors that may have affected the survival were analyzed by logistic regression, to identify significant variables associated with late death. Results Total 561 anastomosis sites of internal mammary arteries were completed with each patient received an average of 3.4 grafts.  There were no perioperative deaths. There were 16 patients with postoperative complications including recurrent angina, myocardial infarction, low cardiac output syndrome, sternal infection and so on. All patients were treated conservatively without reoperation. One hundred sixty patients(97%)were followed up of 5.6±1.2 years, there were 23 late deaths including 10 patients of cardiac related death in which 3 had recurrent myocardial infarction, 4 heart failure, and 3 arrhythmia; 13 patients of nocardiac related death in which 4 upper gastrointestinal hemorrhage, 3 cancer and 6 uncertain cause. 25 patients had major cardiac related events including recurrent angina 18, myocardial infarction 4, repeated revascularization 3. Left ventricular ejection fraction [CM(159mm]was significantly improved as compared with that before operation(54%±6% vs. 43%±12%, Plt;0.05). The 1-, 3-, 5-year actuarial survival rates and eventfree rates were 98.2%±0.3%, 96.2%±0.5%, 90.5%±1.9% and 95.5%±1.2%, 91.3%±2.1%, 86.6%±1.5%, respectively. According to statistical analysis, univariate analyses had proved that advancing age>65 years,diabetes,ejection fraction(EF) less than 30%,the New York Heart Association (NYHA) class Ⅲ/Ⅳ, and low cardiac output syndrome required placement of the intraaortic balloon pump were predictors associated with hospital major adverse cardiac events (Plt;0.05). Those variables entered into the logistic regression model and found to be independent predictors associated with increased late cardiac death included advancing age >65 years(OR=11.6), diabetes (OR=21.4), EF less than 30%(OR=37.5) and NYHA class Ⅲ/Ⅳ(OR=40.2). Conclusion Patients receiving bilateral internal mammary artery composited Y grafts have better longterm survival and reduced cardiac related events. Independent risk factors for late death are NYHA function class Ⅲ/Ⅳ, EF less than 30%, diabetes and advancing age >65 years.

    Release date:2016-08-30 06:06 Export PDF Favorites Scan
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