目的 探讨冠状动脉钙化检测联合动态心电图对冠心病的诊断价值及临床应用。 方法 对2010年5月-2011年8月住院的108例拟诊冠心病的患者同期进行128排螺旋CT冠状动脉钙化积分检测、动态心电图和冠状动脉造影,对比研究冠状动脉钙化检测联合动态心电图预测冠心病的价值。 结果 冠状动脉钙化阳性预测冠心病的灵敏度、特异度、阳性预测值和阴性预测值分别为75.6%、81.0%、73.9%、82.3%;动态心电图阳性预测冠心病的灵敏度、特异度、阳性预测值和阴性预测值分别为73.3%、76.2%、68.8%、80.0%;冠状动脉钙化检测联合动态心电图的系列实验的特异度和阳性预测值分别达到96.8%和92.9%,平行试验的灵敏度和阴性预测值分别达到93.3%和92.7%,均显著高于单项试验的相应指标(P<0.05)。 结论 高分辨率螺旋CT冠状动脉钙化检测联合动态心电图显著提高冠心病的诊断价值,可作为老年患者及基层医院冠心病首选的筛选检查。
目的报告8例肝血管平滑肌脂肪瘤的影像学特征及病理学特点,探讨其诊断与治疗方法。方法对8例经手术及病理证实的肝血管平滑肌脂肪瘤的术前影像学表现(B超、CT、MRI、99mTcPMT)、手术情况及病理特点进行分析。结果B超: 肿瘤呈强回声光团6例,低回声光团2例; 边界清楚7例,血供丰富、内部回声不均匀4例,其中1例内部呈分隔网状结构。彩色Doppler超声示肿瘤血供丰富,均测及动脉频谱,阻力指数为0.4~0.5。静脉造影示肿瘤内血流信号明显增加。CT: 平扫示肿瘤呈低密度影7例,不均匀5例,边界清楚7例,肿瘤内见软组织影2例,脂肪成分2例。增强扫描示动脉期明显强化,门脉期及延迟期逐渐呈低密度。MRI: 肿瘤呈短T1、长T2信号,增强后强化明显,脂肪抑制后短T1变成长T1。99mTcPMT示肿瘤呈放射性增强,5 min相肿块区呈放射性缺损,2 h、5 h延迟相肿块区未见放射性填充,肝血池相肿块呈放射性填充。病理及免疫组化: 肿瘤由成熟的脂肪、血管及平滑肌组成,HMB45阳性。术前确诊3例。结论B超示强回声光团,CT呈低密度影中出现软组织影、脂肪成分,增强明显,MRI出现脂肪信号,脂肪抑制后短T1变成长T1,增强明显。99mTcPMT示肿瘤呈放射性增强,5 min相呈放射性缺损,延迟相未见放射性填充,肝血池相呈放射性填充。这些是肝血管平滑肌脂肪瘤的影像学特点,结合病史可作出诊断。此病应尽早手术治疗,行肝部分切除术。最后确诊依靠病理检查及免疫组化分析。
Objective To testify the spatial relationship between the subscapularis muscle splitting window and the axillary nerve in modified arthroscopic Latarjet procedure, which could provide anatomical basis for the modification of the subscapularis muscle splitting. MethodsA total of 29 adult cadaveric shoulder specimens were dissected layer by layer, and the axillary nerve was finally confirmed to walk on the front surface of the subscapularis muscle. Keeping the shoulder joint in a neutral position, the Kirschner wire was passed through the subscapularis muscle from back to front at the 4 : 00 position of the right glenoid circle (7 : 00 position of the left glenoid circle), and the anterior exit point (point A, the point of splitting subscapularis muscle during Latarjet procedure) was recorded. The vertical and horizontal distances between point A and the axillary nerve were measured respectively. Results In the neutral position of the shoulder joint, the distance between the point A and the axillary nerve was 27.37 (19.80, 34.55) mm in the horizontal plane and 16.67 (12.85, 20.35) mm in the vertical plane. Conclusion In the neutral position of the shoulder joint, the possibility of axillary nerve injury will be relatively reduced when radiofrequency is taken from the 4 : 00 position of the right glenoid (7 : 00 position of the left glenoid circle), passing through the subscapularis muscle posteriorly and anteriorly and splitting outward.
To investigate the biomechanical effects of direct ventricular assistance and explore the optimal loading mode, this study established a left ventricular model of heart failure patients based on the finite element method. It proposed a loading mode that maintains peak pressure compression, and compared it with the traditional sinusoidal loading mode from both hemodynamic and biomechanical perspectives. The results showed that both modes significantly improved hemodynamic parameters, with ejection fraction increased from a baseline of 29.33% to 37.32% and 37.77%, respectively, while peak pressure, stroke volume, and stroke work parameters also increased. Additionally, both modes showed improvements in stress concentration and excessive fiber strain. Moreover, considering the phase error of the assist device's working cycle, the proposed assist mode in this study was less affected. Therefore, this research may provide theoretical support for the design and optimization of direct ventricular assist devices.
Objective To investigate the characteristics of patients with crush injury in Wenchuan earthquake and the corresponding operational methods. Methods From May 12th 2008 to June 18th 2008, 202 patients with crush injury of soft tissue were treated, including 110 males and 92 females. Twenty-five patients aged 19 months to 16 years, 129 patients aged 17-60 years and 48 patients aged above 61 years. The crushed time was 30 minutes to 154 hours. Sixty cases of openinjuries were treated by debridement and dressing or suture; 16 cases of damaged extremities (18 l imbs) and 6 cases of acute renal failure due to crush syndrome (8 l imbs) received amputation; 32 cases of interfascial space syndrome crisis (42 l imbs) were treated by fascia cavity decompression; 15 cases received the resection of necrotic muscle for 31 times; and 9 cases received continuous renal replacement therapy (CRRT). Results All the wounds healed except 2 cases which died from intestinal bleeding and intracranial hemorrhage during the treatment of CRRT. Two cases were discharged 8 months after treatment, while the other 198 cases recovered and were discharged 15-120 days after treatment. The average hospital ization time was 53 days. Twenty-two cases (26 l imbs) were fixed with artificial l imbs 3-6 months after amputation and achieved good functional outcome. Conclusion The treatment principle of crush injury is “be active to decompress and be prudent to amputate”, the hardening muscle and the increasing level of creatine kinase and blood potassium are the golden indicators of fascia cavity decompression. Decompression at an earl ier period is preferred when there is a dilemma to choose, and open amputation should be performed when the necrotic muscle is hard to clear or the necrosis boundary is not distinct.