【摘要】 目的 探讨高压氧联合药物治疗突发性耳聋（sudden deafness， SD）的疗效。 方法 2008年2月-2010年7月，对174例SD患者采用高压氧（治疗压力0.2 MPa）及配合扩血管、营养神经等药物进行治疗，并观察其疗效。 结果 高压氧联合药物治疗SD总有效率为85.7％，SD的发病就诊时间是影响预后的主要因素，发病就诊时间≤7 d时，治疗有效率可达95.6%；≥15 d时，疗效明显降低。 结论 高压氧联合药物治疗SD疗效确切，且高压氧治疗越早疗效越好。 【Abstract】 Objective To observe the therapeutic effect of hyperbaric oxygen combined with medical treatment on sudden deafness. Methods Between February 2008 and July 2010, 174 patients with sudden deafness were treated by a combined therapy, including hyperbaric oxygen and medicals. The therapeutic effect was analyzed. Results The total effective rate was 85.7％. The simultaneous phenomenon such as vertigo and vomiting and onset-diagnosis duration were the two major factors affecting the prognosis. When the onset-diagnosis duration was ≤7 days, the effective rate reached 95.6%; when the onset-diagnosis duration was≥15 days, the therapeutic effect decreased significantly. Conclusion Hyperbaric oxygen combined with medical treatment is effective for sudden deafness, and the hyperbaric oxygen treatment should be performed as earlier as possible.