目的 探讨磁共振扩散加权成像（DWI）、动脉自旋标记技术（ASL）、磁共振血管成像（MRA）联合应用在缺血性脑血管病诊断中的价值。 方法 对2010年3月－2012年5月经临床和影像学诊断的104例缺血性脑血管病患者，行常规MRI、液体衰减反转恢复序列、DWI及ASL、MRA序列检查，分析DWI、ASL、MRA多种技术显示病变的信号特征、面积大小及与血管关系。 结果 DWI对急性及亚急性脑梗死的检出率为100%，对大、小面积梗死病灶检出率无明显差异；ASL对大、小面积的急性及亚急性脑梗死的检出率有差异，对大面积梗死检出率为100%，对小面积梗死的检出率为70%；DWI和ASL对短暂性脑缺血发作的检出率分别为0%、70%，液体衰减反转恢复序列对短暂性脑缺血发作患者大脑皮层下斑状缺血灶检出最敏感。 结论 DWI和ASL均可用于急性脑梗死的早期诊断，ASL对大、小面积的急性及亚急性脑梗死的检出率有差异，DWI、ASL及MRA联合应用可准确评估缺血半暗区及侧支血管情况，在缺血性脑血管病诊断中有重要价值。
【摘要】 目的 探讨常规MRI扫描及胰胆管造影（MRCP）对胆管梗阻性疾病的临床诊断价值。 方法 2006年4月-2010年6月，对59例胆管梗阻性疾病患者行常规MRI及MRCP检查，其中18例行动态增强扫描，并与临床诊断或手术、病理结果对照分析。MRCP采用不屏气厚层快速自旋回波（FSE）序列重度T2WI扫描，原始图像以最大信号强度投影（MIP）法进行三维重建。 结果 MRI及MRCP对胆管梗阻程度的判断和定位诊断准确率为100.0%，定性诊断准确率为91.5%，其中MRCP诊断胆管结石和恶性胆管梗阻的准确率分别为96.8%和86.9%。 结论 MRCP对胆管梗阻的定位诊断准确，结合3D原始图像、常规MRI扫描及动态增强扫描，对胆管结石和恶性胆管梗阻的定性诊断有很高的准确性。【Abstract】 Objective To evaluate the clinical diagnosis value of MRI and cholangiopancreatography (MRCP) in diagnosis of biliary obstructive disease. Methods Routine MRI and MRCP were performed on 59 patients between April 2006 and June 2010, in which dynamic enhance scan was performed on 18 patients. The results were compared with clinical diagnosis or surgical findings and pathological examination. Non-breath-hold thick slices heavy T2 weighted TSE sequence was used. The original images were reconstructed by using three-dimensional maximum-intensity-projection (MIP) algorithm. Results The accuracy of MRI and MRCP in the detection of the degree and level of bile duct obstruction was 100.0 % and the accuracy for evaluating the causes of obstruction was 91.5 %. In the diagnosis of bile duct stone and malignant biliary obstruction, the diagnostic rate of MRCP was 96.8 % and 86.9%. Conclusion Routine MRI and MRCP examination can accurately define the level of bile duct obstruction. Combining with the original images and routine images and dynamic enhance scan, the specificity for the diagnosis of bile duct stone and malignant biliary obstruction is high.