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find Keyword "Acute respiratory distress syndrome" 1 results
  • The Application of Lungprotective Strategies of Ventilation for Patients with Acute Respirator Distress Syndrome after Thoracic Operation

    Objective To evaluate the efficacy of lung-protective strategies of ventilation (LPSV) in acute respiratory distress syndrome (ARDS) patients after thoracic operation. Methods-Thirtyseven ARDS patients without preoperative complications who had underwent thoracic surgery successfully were divided into the conventional mechanical ventilation group (CMV group, n=20) and lungprotective strategies of ventilation group (LPSV group,n=17). Results of arterial blood gas, index of oxygenation (PaO2/FiO2), airway plateau pressure (Pplat), inspiration peak pressure (PIP), PEEP, after ventilation treatment 24 h and mechanical ventilation time, pulmonary barotrauma and so on were observed. Results The mechanical ventilation time, pulmonary barotrauma and mortality of the LPSV group were 7.3d, 5.9% and 29.4% respectively, which were significantly better than those in the CMV group(17.6d,15.0% and 60.0%, Plt;0.05). peak inflation pressure (PIP),Pplat(plat pressure) in the LPSV group were significantly lower than those in the CMV group (Plt;0.05). However, there were no significant differences including arterial oxygen saturation (SaO2),pH, partial pressure of carbon dioxide in artery (PaCO2) and PaO2/FiO2 in two groups. Conclusion LPSV is more effective for the patients in the ARDS patients after thoracic operation compared to CMV, which can markedly reduce the ventilatorinduced lung injuryand (VILI) and mortality.

    Release date:2016-08-30 06:08 Export PDF Favorites Scan
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