Objective To explore the application of artificial intelligence in the risk assessment and diagnosis of pancreatic cancer, and to point out its limitations and future suggestions, so as to promote the further application of artificial intelligence in the future. Method The related literatures on the application of artificial intelligence in the risk assessment and diagnosis of pancreatic cancer at home and abroad in recent years were reviewed. Results The usage of artificial intelligence models to assess high-risk patients was beneficial to the diagnosis of pancreatic cancer, although more data were needed to support its role in pancreatic cancer screening. In terms of early diagnosis, artificial intelligence technology could rapidly locate high-risk groups through medical imaging, pathological examination, biomarkers, and so on, and then detected pancreatic cancer at an early stage. Conclusion Despite some limitations, artificial intelligence will play an important role in the early diagnosis and risk prediction of pancreatic cancer in the future due to its powerful computational power.