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find Author "CHEN Xinsheng" 1 results
  • Immunohistochemical Study about Expression of Caspase-3 in Hemangiomas

    ObjectiveTo study the relationship between expression of Caspase-3 and regression of hemangioma. MethodsCaspase-3 expression was detected in 79 hemangiomas and 5 normal skin tissues by immunohistochemistry (SP). ResultsIn 79 hemangiomas, the positive rates of Caspase-3 expression in proliferating, involuting and involuted phases were 52.4%, 91.2% and 83.3%, respectively. The expression of Caspase-3 in involuted and involuting phases was higher than proliferating phase(Plt;0.05,Plt;0.01) and control group(Plt;0.01). There was no statistical difference between the latter two groups (Pgt;0.05). ConclusionCaspase3 is involved in the converting of hemangiomas from proliferating phase into involuting phase. The activation of Caspase-3 may induce apoptosis of endothelial cells, thus leading to the regression of hemagioma.

    Release date:2016-08-28 04:43 Export PDF Favorites Scan
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