ObjectiveTo summarize the characteristics and biomechanical research progress of common internal fixation for femoral neck fractures in recent years, so as to provide reference to clinical treatment of femoral neck fracture. Methods The domestic and foreign relevant literature on biomechanics of internal fixation of femoral neck fracture in recent years was reviewed, and the biomechanical research progress was summarized. Results Among the internal fixations currently used in the treatment of femoral neck fractures, three cannulated screws can provide sliding compression at the end of the fracture, but the shear resistance is weak, and the risk of long-term internal fixation failure is high; dynamic hip screw and proximal femoral locking plate have excellent angle stability and overall strength; medial buttress plate can transform vertical shear force into compressive stress to promote fracture healing and produce a certain anti-rotation effect; femoral neck system can support the fracture in multi-axial direction, with excellent anti-rotation and anti-shortening properties; and cephalomedullary nails have high overall strength and failure load. Different internal fixations have their own indications due to differences in structure and biomechanics. ConclusionAt present, there is no detailed standard guidance of internal fixation selection. Clinically, the appropriate treatment should be selected according to the fracture types of patients.
Objective To summarize the characteristics and biomechanical research progress of common acetabular reconstruction techniques in patients with Crowe type Ⅱ and Ⅲ developmental dysplasia of the hip (DDH) undergoing total hip arthroplasty (THA), and provide references for selecting appropriate acetabular reconstruction techniques for clinical treatment of Crowe type Ⅱ and Ⅲ DDH. Methods The domestic and foreign relevant literature on biomechanics of acetabular reconstruction with Crowe type Ⅱ and Ⅲ DDH was reviewed, and the research progress was summarized.Results At present, there are many acetabular reconstruction techniques in Crowe type Ⅱ and Ⅲ DDH patients undergoing THA, with their own characteristics due to structural and biomechanical differences. The acetabular roof reconstruction technique enables the acetabular cup prosthesis to obtain satisfactory initial stability, increases the acetabular bone reserve, and provides a bone mass basis for the possible secondary revision. The medial protrusio technique (MPT) reduces the stress in the weight-bearing area of the hip joint and the wear of the prosthesis, and increases the service life of the prosthesis. Small acetabulum cup technique enables shallow small acetabulum to match suitable acetabulum cup to obtain ideal cup coverage, but small acetabulum cup also increases the stress per unit area of acetabulum cup, which is not conducive to the long-term effectiveness. The rotation center up-shifting technique increases the initial stability of the cup. Conclusion Currently, there is no detailed standard guidance for the selection of acetabular reconstruction in THA with Crowe type Ⅱ and Ⅲ DDH, and the appropriate acetabular reconstruction technique should be selected according to the different types of DDH.
Real world data (RWD) and real world evidence (RWE) have increasingly received wide attention. Patient registry study is an important part of real-world studies using observational design. In this paper, we introduce the concept, classification and application of patient registries, and discuss the planning for a patient registry study and development of registry database, and provide methodological guidance for developing high-quality patient registry studies.
Retrospective database study is an important type of real world study that employ observational designs, which has received wide attention. However, misunderstandings and inappropriate conduct of retrospective database studies are very common. We systematically introduced the concept, features and applications of retrospective database study, as well as discussed the methods to plan a retrospective database study and how to develop a research database. This article is expected to offer guidance for the quality production and appropriate use of retrospective database study.