Purpose To investigate the therapeutic effect and complications of vitreous surgery in conjunction with laser treatment for high myopic retinal detachment with macular hole． Methods Thirtyfive consecutive cases(38 eyes) of high myopic retinal detachment with macular hole in our institute from January 1994 to August 1997 were analysed retrospectively.Among them,11 cases(12 eyes)were treated with vitreous operation and 24 cases (26 eyes)with vitreous operation combined with argon laser photocoagulation of the macular holes.All of the eyes operated on were followed up for more than 6 months,and with an average period of 21.7 months. Results In the 12 nonlaser treated eyes the macular hole recured in 5 eyes (41.7%),and the visual acuity was 20/200 or more in 6 eye(50.0%).In the 26 laser treated eyes,the macular hole recurred in 2 eyes(7.7%),new retinal tear appearred in 1 eye, and the visual acuity was 20/200 or more in 13 eyes(50.0%).The probability of recurrence of the macular hole between nonlaser and laser treated eyes was 0.024,and of retinal probability redetachment between them was 0.0487.There was no significant difference in between pre and postoperative visaul acuity. Conclusion Vitreous surgery in conjunction with laser photocoagulation for high myopic retinal detachment with macular hole might be helpful in improving the operative successful rate. (Chin J Ocul Fundus Dis,1998,14:199-201)