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find Author "DONG Liguo" 1 results
  • Comparison of the Change of T-Lymphocyte Subsets and Immunoglobulin in Postoperative Gastric Carcinoma Patients with Regional Intra-Artery Implantation Pump Chemotherapy Versus Peripheral Venous Chemotherapy

    Objective To observe the turbulence of regional intra-artery implantation chemotherapy and peripheral venous chemotherapy on immunologic function of patients. Methods Two weeks after radical operation of gastric carcinoma, chemotherapy was performed. Eighty-three patients were divided into two groups, one (42 patients) received peripheral venous chemotherapy (PVC) and the other (41 patients) received regional intra-artery implantation pump chemotherapy (RAIPC). The serum T-lymphocyte subsets and immunoglobulin level before and 1-4 days after the chemotherapy were measured. Results After PVC, proportion of CD3 and CD4, CD4/CD8 and IgG, IgA, IgM concentration in PVC group were significantly decreased compared with those before PVC (P<0.05, P<0.01), and it is the same when compared with postRAIPC patients except for CD4 and IgM (P<0.05). In RAIPC group, there were no significant changes in proportion of CD3, CD4 and CD8, CD4/CD8 and IgG, IgA concentration between pre- and post-RAIPC patients. Conclusion After radical operation of gastric carcinoma, RAIPC affects the immunologic function more moderate than PVC.

    Release date:2016-08-28 04:43 Export PDF Favorites Scan
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