Objective To explore the status of women’s quality of life and analyze risk factors related diminished ovarian reserve (DOR). Methods We applied the method of convenient sampling to investigate 61 patients with DOR (DOR group) and 60 women with normal ovarian reserve function (control group) who visited a reproductive centre of a Triple-A hospital from February to May 2013, using a questionnaire which included basic information table, Menopausal Quality of Life Scale (MENQOL) and SF-36 Health Survey for quality of life, and Kupperman Index Scale (KI) for the degree of clinical symptoms. Then, statistical analysis was performed using SPSS 17.0 software. Results Compared with the control group (43.60±16.82), the level of women’s quality of life in the DOR group (73.42±24.15) was significantly lower (Plt;0.01), while the degree of clinical symptoms was significantly higher (Plt;0.01). There were positive associations between quality of life and degree of clinical symptoms. The risk factors related to DOR were various such as age, weight, quality of sleep, menstrual disorders, number of abortion, age of the first pregnancy, gynecologic surgery, economic income, education, family relationship, unsatisfactory sexual life, and psychological factors. Conclusion In order to improve women’s quality of life, effective treatment should be conducted to relieve clinical symptoms of women with DOR. Good life style, harmonious family relationship, healthy mind and avoiding the risk factors, which could effectively help the prevention and treatment of the disease.
Objective To compare the outpatient in gynecology department with health screening women in aspects of general condition, bearing, livelihood, economics and family, and to analyze the factors that relate to premature ovarian failure (POF) and diminished ovarian reserve (DOR). Method To survey 178 outpatients of gynecology department and health screening women visited from January to December of 2007, and to investigate the possible related factors through a questionnaire including the condition of basic information (e.g. age, marital status, occupation and education), menstruation, pregnancy and delivery, contraception, health, livelihood, economics, psychology, society, family and so on. The data were analyzed with SPSS 13.0 software. Results A total of 45 POF patients, 83 DOR patients and 50 healthy women were included. The results of questionnaire showed that the physiological factor was the main reason for the occurrence of POF and DOR; the menstrual disorders, autoimmune diseases (such as systemic lupus erythematosus, idiopathic thrombocytopenic purpura, glomerulonephritis, rheumatoid arthritis, etc.), malignancy cancer, pelvic surgery, smoking and drug abuse, and lack of sleep were closely related to POF and DOR; the social and psychological factors were other main reasons to cause POF and DOR. Conclusion The onset of both POF and DOR is caused by many factors, such as physical, social and psychological factors. The effective prevention and treatment for these diseases should be conducted positively in accordance with these three aspects.