ObjectiveTo summarize the developments of oxygen-generating materials as biomaterials and its applications in tissue engineering. MethodsThe recent literature on oxygen-generating materials as biomaterials was extensively reviewed, illustrating the properties and applications of oxygen-generating materials in tissue engineering. ResultsOxygen-generating materials as biomaterials have good biocompatibility and degradability. It supports the cell adhesion differentiation and growth. It is used for repairing liver, pancreas, myocardium, and so on. After modification, oxygen-generating materials can be extensively used in tissue engineering. ConclusionOxygen-generating materials is a good biomaterial, which has a great potential applications in tissue engineering.
ObjectiveTo systematically review the methodological quality of guidelines on the management of bronchiolitis in children, then to compare the recommendations and to provide a reference for clinical use. MethodsGuidelines concerning bronchiolitis were electronically retrieved in CNKI, VIP, WanFang Data, CBM, PubMed, EMbase, Medlive, GIN (Guidelines International Network), CGC (China Guideline Chearinghouse), NGC (National Guideline Clearinghouse), AAP (American Academy of Pediatrics), NICE (National Institute for Health and Clinical Excellence) and WHO (World Health Organization) from inception to December 2015. The methodological quality of included guidelines were evaluated according to the AGREE II instrument, and the differences between recommendations were compared. ResultsEight guidelines on bronchiolitis were included, Among them, one guideline was developed by UK, two by US, one by Spain, two by Australia, one by Scottish and one by South Africa. Five of them were evidence-based (EB) guidelines, and 3 were non-EB guidelines. Domain 4 (clarity of presentation) showed the highest scores (81%), then scope and purpose (74%), stakeholder involvement (56%), rigor of development (52%), editorial independence (43%), and scores (42%) were the lowest in domain 3 (applicability). The recommendations of managements and medicines for bronchiolitis were basically consistent, but there were individual differences suggested. ConclusionIn these guidelines, the domain score better is "clarity of presentation" and "scope and purpose ", but the other areas should need to improve. Current our country only has an expert consensus of bronchiolitis, which should be further improved. It's urgent to develop evidence-based guidelines which conforms to the situation of our country, in order to make evidence-based medicine implementation in clinical practice.
ObjectiveTo systematically review the methodological quality of clinical practice guidelines (CPGs) on the management of acute gastroenteritis/diarrhea in children, then to compare differences and similarities of drug recommendations, in order to provide references for clinical practice. MethodsGuidelines concerning acute gastroenteritis/diarrhea in children were searched in CNKI, VIP, WanFang Data, CBM, PubMed and EMbase databases from inception to April 2015. The websites of GIN (Guidelines International Network), CGC (China Guideline Clearinghouse), NGC (National Guideline Clearinghouse), APP (American Academy of Pediatrics), NICE (National Institute for Health and Clinical Excellence) and the WHO (World Health Organization) were also searched for additional guidelines. The methodological quality of included guidelines were evaluated according to the AGREE Ⅱ instrument, and the differences between recommendations of included guidelines were compared. ResultsA total of 9 guidelines on acute gastroenteritis/diarrhea in children were included. Among them, 3 guidelines were developed by USA, 1 by Malaysia, 1 by EU, 1 by UK, 1 by South Wales, 1 by Australia and 1 by South Africa. Five guidelines were evidence-based guidelines, and the other 4 were non-evidence-based guidelines. The average scores of guidelines in six domains of AGREE Ⅱ were 79% (clarity of presentations), 74% (scope and purpose), 44% (stakeholder involvement), 35% (rigor of development), 32% (applicability), and 30% (editorial independence), respectively. The recommendations of management and treatment were almost consistent. ConclusionThe overall quality of included guidelines was not high. The domain scores of "clarity of presentations" and "scope and purpose" were higher, but the domain scores of "stakeholder involvement", "rigor of development", "applicability" and "editorial independence" needed to be improved. There is still no local guideline of acute gastroenteritis/diarrhea in children in China, so it's urgent to develop guideline that should be suite able for Chinese condition.
ObjectiveTo survey on the health-related knowledge in cadres, in order to regulate corresponding health management strategies. MethodsQuestionnaires were used to collect data of 816 examinees who accepted physical examination in our hospital between June and July 2014. Factors affecting health examination service efficiency were identified to formulate a scale and a questionnaire for surveying examinees' preparatory status before examination and general information. The correlation between their preparatory status and demographic features was analyzed. The results were used to support management decision-making. ResultsOf the 816 examinees, 396 had a score over 6 points (48.5%, well prepared) and 420 had 6 points or below (51.5%, poorly prepared). The male preparation before examination was significantly poorer than the female (χ2=4.318, P=0.038). ConclusionWe should strengthen the knowledge education for cadres before physical examination.