ObjectiveTo explore the effect of humanistic nursing care on patients in the Emergency Department. MethodsBetween May and August 2013, 166 acute patients were randomly divided into trial group and the control group (83 patients in each group). The patients in the control group received routine nursing care, while the patients in the trial group were given routine and humanistic nursing care. The patient's satisfaction of nursing skill and work attitude, grasp of disease related knowledge, compliance, and disease control effec were compared between the two groups. ResultsThe patient's satisfaction, grasp of disease related knowledge, compliance, disease control effect in the experiment group were superior to the control group (P<0.05). ConclusionThe implementation of humanistic nursing care on patients in Emergency Department is effective, and it's worthy of clinical promotion.