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find Author "HU Zhan" 1 results
  • Comparison of Accuracy of Different Renal Function Measurements for Predicting Adverse Events after Off-pump Coronary Artery Bypass Grafting

    Objective To compare the accuracy of different renal function measurements for predicting postoperativeadverse events after off-pump coronary artery bypass grafting (OPCAB) for Chinese patients. Methods Clinical data of 283 Chinese patients undergoing isolated OPCAB from January 2010 to December 2011 in the First Hospital of Peking University were retrospectively analyzed. There were 194 male and 89 female patients with their age of 65.0±9.7 years. Estimated glomerular filtration rate (eGFR) was calculated using Cockcroft-Gault equation,Modification of Diet in Renal Disease (MDRD) study equation and Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation respectively.Logistic multivariate regression analysis was performed to compare the accuracy of these 3 different renal function measure-ments for predicting postoperative adverse events. Results Logistic multivariate regression analysis showed that preoper-ative renal dysfunction was an independent risk factor for higher postoperative morbidity,more blood transfusion,prolongedhospitalization,mechanical ventilation time and length of ICU stay. Among the different postoperative complications,preop-erative renal dysfunction was an independent risk factor for postoperative acute renal injury,gastrointestinal bleeding,new onset atrial fibrillation and low cardiac output syndrome. Among Cockcroft-Gault equation,MDRD study equationand CKD-EPI equation to calculate eGFR,CKD-EPI equation was most accurate to predict postoperative morbidity (OR=1.227),acute renal injury (OR=1.534),new onset atrial fibrillation (OR=1.184),prolonged hospitalization(OR=1.160),mechanical ventilation time (OR=1.165) and ICU stay (OR=1.151). Conclusion Preoperative renal dysfunction is an independent risk factor for postoperative adverse events after OPCAB. CKD-EPI equation is more suitable for predicting postoperative adverse events after OPCAB for Chinese patients.

    Release date:2016-08-30 05:47 Export PDF Favorites Scan
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