In recent years, cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) have been increasingly used for the treatment of peritoneal metastases. Imaging examination plays an important role in the process of CRS+HIPEC in treatment of peritoneal metastasis. This article briefly introduces the preoperative imaging evaluation, postoperative imaging evaluation, and current limitations of CRS+HIPEC in the treatment of peritoneal metastases.
ObjectiveTo summarize the common imaging features of liver cancer after local-regional therapy in order to more accurately evaluate the post-treatment response of it. MethodThe literatures of studies on imaging features after ablation, transcatheter therapy, and radiotherapy of liver cancer in recent years were searched and reviewed. ResultsIt was not accurate to evaluate the response of liver cancer after treatment only by comparing the size of tumor before and after treatment. We should follow up and observe the changes of enhancement components after tumor treatment, and pay attention to identify the normal features after treatment. ConclusionsImaging evaluation after local-regional therapy of liver cancer is of great significance in management and clinical decision-making of patients with liver cancer. Standard response evaluation systems such as EASL or mRECIST should be carefully applied after local-regional therapy of liver cancer. Treatment response of patients should be comprehensively evaluated in combination with the characteristics of local-regional therapy methods and timing, so as to avoid delaying timing of secondary treatment and causing excessive treatment.
Objective To assess the clinical efficacy of neoadjuvant chemotherapy (NAC) for breast invasive ductal carcinoma with MR diffusion weighted imaging. Methods Thirty patients with breast invasive ductal carcinoma underwent conventional MRI scanning and diffusion weighted imaging examination before and after preoperative neoadj-uvant chemotherapy. Two experienced radiologists independently analyzed and measured the maximum lesion diameter and apparent diffusion coefficient (ADC) values before and after treatment,respectively. Statistical analysis was performed for testing the tumor maximum diameter and ADC values change by using the paired t-test. Results After NAC treatment,the maximum tumor diameter of invasive ductal breast carcinoma sharply reduced〔(4.33±0.83) cm vs. (2.04±0.64) cm,P<0.001〕. When b value was 1 000,the mean ADC values of breast massess were significantly changed after NAC treatment〔(1.89±0.15) ×10-3mm2/s vs. (1.14±0.31) ×10-3mm2/s, P<0.05〕. Conclusion MR diffusion weighted imaging can non-invasively and accurately assess the NAC efficacy, which are helpful for making surgical strategies.
Objective To assess the significance of multi-detector row CT in differential diagnosis of the inguinal hernia and femoral hernia. Methods CT images which were reconstructed by multi-planer reconstruction (MPR) of 260 patients with inguinal hernia and femoral hernia who treated in our hospital form Oct. 1, 2012 to Oct. 31, 2013 were analyzed retrospectively, for exploring the relationship between sac and anatomic structure in the groin area. Results There were 146 patients with indirect hernia (75 in right, 60 in left, and 11 in bilateralism), 82 patients with direct hernia(39 in right, 34 in left, and 9 in bilateralism), and 32 patients with femoral hernia (17 in right and 15 in left). The 157sacs of patients with indirect hernia originated lateral to the inferior epigastric artery, entered the inguinal canal and through the deep ring, which mainly located anterior (103/157, 65.6%) or anteromedial (36/157, 22.9%) to the spermatic cord or round ligament. The 91 sacs of patients with direct hernia originated medial to the inferior epigastric artery, and mainly located medial to the spermatic cord (70/91, 76.9%). Sacs of both indirect hernia and direct hernia located anterosuperior to the inguinal ligament. The 32 sacs of patients with femoral hernia located posterior to the inguinal ligament and inside the “radiological femoral triangle” of coronal views. Conclusions The MPR images available from multi-detector row CT permit the accurate diagnosis of groin hernias. By using simple anatomical criteria, direct hernia, indirect hernia, and femoral hernia can be reliably distinguished.
Objective To investigate the situation and prospect of local recurrence of rectal cancer by using CT and MRI. Method Relevant references about the imaging diagnosis of local recurrence of rectal cancer, which were published domestic and abroad in recent years, were collected and reviewed. Results In the diagnosis of local recurrence of rectal cancer, the sensitivity of CT was higher than that of MRI, while the specificity and accuracy were not. Perfusion CT, dynamic contrast-enhanced MRI, and diffusion weighted imaging were valuable in diagnosing local recurrence of rectal cancer, as new diagnostic techniques. Conclusion Both CT and MRI are important and valuable methods in diagnosing for local recurrence of rectal cancer.
Objective To investigate the magnetic resonance imaging (MRI) assessment and functional evaluation of chronic pancreatitis (CP). Methods Literatures about MRI assessment of CP (especially the evaluation of pancreatic exocrine function with MRI) were reviewed. Results Some early parenchymal changes (pancreatic size,signal intensity of pancreas, and enhancement pattern) in the CP could be visualized by MRI;ductal changes could be visualized by MR cholangiopancreatography (MRCP);and secretin-stimulated MRCP (combination of both morphologic and functional evaluation) not only improved the visualization of pancreatic duct and side branches,but also allowed evaluation of the pancreatic exocrine function noninvasively. Secretin-stimulated diffusion weighted imaging also could be used as a noninvasive method to assess pancreatic exocrine function. Conclusions Conventional MRI and (or) secretin-stimulated MRI can become valuable means in CP (especially early-stage CP), with furnishing morphologic and functional information simultaneously. However,further research is needed to verify the diagnostic accuracy of these modalities.
Objective To summary the principle of magnetic resonance spectroscopy imaging and its application progress in diagnosis and differential diagnosis of pancreatic cancer. Methods The newest related literatures of home and abroad were collected and reviewed. Results Magnetic resonance spectroscopy imaging was a technology using the magnetic resonance phenomena and chemical shift phenomena to measure molecular organization. The spectroscopy most commonly used in clinical and scientific research includes 1H, 31P, and 23Na. Conclusion Magnetic resonance spectroscopy as the only approach to noninvasive quantitative provding biochemical information in vivo, has an important significance to the diagnosis and differential diagnosis of pancreatic cancer.
Objective To assess the radiation dose and image quality with low-dose multi-detector row CT urography (CTU) for the evaluation of children patients with ureteropelvic junction stenosis (UJS). Methods In this prospective study, 30 children patients with UJS underwent CTU were classified half-randomly through exam numbers into 3 groups (115 mA, 100 mA, and 75 mA). Consecutive acquisitions including CT dose index weighted (CTDIw) and dose long product (DLP) were obtained in each patient and compared for each group. Three experienced chest radio-logists were unaware of the CT technique reviewed CT images for overall image quality using a 3-grade scale (excellent, good, and worst). The data were analyzed using a parametric analysis of variance test and Wilcoxon’s signed rank test. Results The CTDIws of 115 mA group, 100 mA group, and 75 mA group were (7.63±0.83) mGy, (6.29±0.51) mGy, and (4.72±0.18) mGy, respectively, the difference was significant among three groups (F=36.445, P=0.000). The mean CTDIw reduction was 38.2% in the 75 mA group as compared with 115 mA group (P<0.001). The DLPs of 115 mA group, 100 mA group, and 75 mA group were (173.89±29.88) mGy•cm, (145.96±26.21) mGy•cm, and (102.78±12.72) mGy•cm, respectively, the difference was significant among three groups (F=13.955, P=0.000). The mean radiation dose reduction was 40.9% (75 mA group versus 115 mA group, P<0.001). The assessment of image quality was no significant difference with the same protocol and post-processing technique (Wilcoxon’s signed rank test, P>0.05). There was a good agreement for image quality scoring among the three reviewers (Kappa=0.736). Conclusion Low-dose multi-detector row CTU should be considered as a promising technique for the evaluation of children patients with UJS because it could decrease radiation dose and obtain acceptable image quality.
Objective To investigate the CT and pathological findings of adrenal myelolipoma, so as to improve the accuracy of diagnosis. Methods CT manifestations of twelve cases with pathological documented adrenal myeloli-pomas were retrospectively analyzed. Combined with pathological features, the location, size, shape, density, and surro-unding structures of adrenal myelolipomas were evaluated on CT image, respectively. Results Of 12 cases with adrenal myelolipomas, 9 cases arose from right adrenals, 2 cases from the left,and 1 case involved bilateral adrenal glands. CT features delineated the mixed density masses arising from adrenals, but majority components were fat densities. Pathological examination demonstrated the tumor was composed of mature fat cells and bone marrow cells. Compared with pathologic results, preoperative CT diagnosis was reliable for significant accuracy (11/12). Conclusions Adrenal myelolipoma is rare. Combined with pathological characteristics clinical findings and laboratory tests, adrenal myelolipoma can be corr-ectly diagnosed with CT examination.
Objective To evaluate the sensitivity, specificity, and accuracy of magnetic resonance imaging (MRI) in characterizing adnexal masses. Methods The databases such as the Cochrane Library, PubMed, EMbase, CNKI, and WanFang Data were searched on computer from 1991 to 2011. The reviewers screened the trials according to inclusion and exclusion criteria strictly, extracted the data, and assessed the methodology quality. Meta-analysis were performed using the Metadisc 1.40 software. The acquired pooled sensitivity, specificity, and summary receiver operating characteristic curve (SROC) were used to describe the diagnostic value. The pooled likelihood ratios were calculated based on the pooled sensitivity and specificity. Results Ten case-control studies involving 649 women who were suspected to have pelvic masses were included and 729 masses were confirmed by the postoperative histopathology. The pooled statistical results of meta-analysis showed that:the sensitivity and specificity of MRI were 〔89%(84%-92%), P=0.046 6〕 and 〔87% (83%-90%), P=0.000 2〕 respectively, the positive and negative likelihood ratios of MRI were 6.25(P=0.008 5) and 0.14(P=0.029 1) respectively, and the area under the SROC curve (AUC) was 0.941. The sensitivity and specificity of ultrasound were 〔87%(82%-91%), P=0.000 0〕 and 〔73%(69%-77%), P=0.000 0〕 respectively, the positive and negative likelihood ratios of MRI were 3.07(P=0.000 0) and 0.18(P=0.000 1) respectively, and the AUC was 0.897. The speci?city and accuracy of MRI in characterizing female pelvic masses were higher than ultrasound obviously. Conclusion According these evidences, the MRI should be recommended to the women who are suspected to have pelvic masses as a preferred.