Objective To investigate the influence of preoperative enteral nutrition with dietary fiber on the nutritional status of patients with colon colostomy diaplasis, and discuss its safety. Methods Forty preoperative colon colostomy diaplasis patients from West China Hospital treated between September 2013 and June 2014 were randomly assigned into trial group and control group with 20 in each. The baseline of the two groups was the same (all P > 0.05). The trial group was given enteral nutrition with dietary fiber before operation for seven days, while control group was given homogenate diet with equal quantity of energy and nitrogen content for the same period of time. All patients were being tested for nutritional indexes on the day of admission and on the fifth day after surgery. Meanwhile, other indexes such as the first time of flatus and defecation, abdominal distension, bellyache, and other adverse reactions were recorded too. Results There was no statistical difference in nutritional indexes on the day of admission and on the fifth day after surgery between two groups (P > 0.05). Patients with dietary fiber had significantly higher incidence of abdominal distension than the control subjects (P < 0.05), but other adverse reactions had no statistical differences between the two groups (P > 0.05). No anastomotic leakage occurred in both the two groups. Patients with dietary fiber had significantly earlier time of flatus than the control group (P < 0.05). Patients with dietary fiber had significantly lower incidence of diarrhea than the control subjects (P < 0.05). Conclusions The study suggests that it is safe and feasible to use enteral nutrition with dietary fiber for preoperative colon colostomy diaplasis patients. Using dietary fiber is helpful for intestinal function recovery and reduction of the occurrence of adverse reactions after surgery.
Objective To explore the effects of early enteral nutrition therapy combined with micro-ecologicalpreparation on early intestinal function recovery in patients with severe acute pancreatitis (SAP). Methods The clinical data of 48 patients with SAP treated from January 2012 to January 2015 were retrospectively analyzed. Out of the 48 cases, 23 were treated with early enteral nutrition therapy (the control group), and 25 were treated with early enteral nutrition therapy combined with micro-ecologicalpreparation (the observation group). The counts of white blood cells (WBC), the levels of blood amylase, serum lipase, lactic dehydrogenase (LDH), and the scores of gastrointestinal function 1 day before treatment and on the 7th and 14th day of treatment were observed. The incidences of complications, case fatality rates, and lengths of hospital stay were recorded. Results One day before treatment, the differences in the counts of WBC, the levels of blood amylase, lipase, and LDH between the two groups were not statistically significant (P>0.05). On the 7th day of treatment, the counts of WBC, the levels of blood amylase, lipase, and LDH in the two groups decreased in varying degrees, and the decreasing in the observation group was more obvious (P<0.05). On the 14th day of treatment, the levels of blood amylase in the two groups were almost normal, and the difference between the two groups was not statistically significant (P>0.05); the levels of lipase, LDH and the counts of WBC in the observation group were lower than those in the control group (P<0.05). One day before treatment, the difference in the scores of gastrointestinal function between the control group (1.34±0.76) and the observation group (1.46±0.62) was not statistically significant (P>0.05); on the 7th and 14th day of treatment, the scores of gastrointestinal function in the observation group (0.37±0.18, 0.29±0.06) were lower than those in the control group (0.63±0.32, 0.47±0.08), and the differences were statistically significant (P<0.05). There were significant differences between the two groups in terms of the incidence of total complications and length of hospital stay (P<0.05), while the difference in the case fatality rate between the two groups was not statistically significant (P>0.05). Conclusion Early enteral nutrition combined with micro-ecological preparation is benefit to the intestinal function recovery in patients with SAP.