【摘要】 目的 探讨低位下颈椎前方入路联合胸骨柄劈开术治疗颈胸段脊柱结核的手术方式及术后疗效。 方法 2002年3月-2009年7月收治颈胸段脊柱结核16例，男11例，女5例；年龄18~52岁，平均38岁。其中位于颈6-胸1者2例，颈7-胸1者5例，胸1-2者4例，胸2-3者3例，胸1-3者2例。神经功能Frankel分级为：B级4例，C级7例，D级3例，E级2例。手术行低位下颈椎前方入路联合胸骨柄劈开术，术中彻底清除结核肉芽组织、脓液、死骨并进行脊髓减压，取自体髂骨块植骨重建中前柱、前方钛板内固定。术后佩戴头颈胸支具6个月，正规抗痨18个月。术前后凸Cobb角为25~60°，平均为37.5°。 结果 全部患者均获得随访，随访时间2~8年，平均3年。均获得骨性融合，融合时间为5～8个月，无螺钉松动、脱落及钢板断裂等并发症发生。神经功能恢复按Frankel分级，平均改善3.6个级别；结核病变无复发，术后后凸Cobb角明显改善，为15～35°，平均22.6°，末次随访后凸角无明显丢失。1例术后出现暂时性声音嘶哑，术后1个月恢复。 结论 低位下颈椎前方入路联合胸骨柄劈开术治疗颈胸段脊柱结核，病灶显露充分，植骨内固定，重建脊柱稳定性，矫正后凸畸形可靠。【Abstract】 Objective To explore the clinical characteristics of cervico-thoracic junction spinal tuberculosis (CTJST) and to observe the therapeutic effect of lower anterior cervical approach combined with presternum-splitting approach on CTJST. Methods The clinical data of 16 patients with cervicothoracic junction spinal tuberculosis from Match 2002 to July 2008 were retrospectively analyzed. According to the Frankel grades, four patients were in grade B, seven were in grade C, three were in grade D, and two were in grade E. There were 11 males and five females with a average age of 38 years ranging from 18 to 52 years. All patients underwent radical excision of epidural granulation tissue/abscess and necrotic bone, whilst a proper tricortical iliac crest autograft and anterior titanium plate were placed to reconstruct the anteromedian spinal column, followed by chemotherapy for 18 months and immobilization in a brace for six months. The mean Cobb angle was 37.5° (ranged from 25° to 60°) before surgery. Results All patients were followed up for two to eight years (three years on average), and got complete bone fusion within five to eight months postoperatively. There were no pull out and breakage of screws or plates.Spinal cord functional recovery improved on average 3.6 degree according Frankel standard, without recurrence of the disease or loss of Cobb angle till the last follow up. There was a statistically significant improvement in the Cobb angles from 22.6° to 37.5° (Plt;0.01) in average. However, two patients appeared transient hoarse voice after surgery, and the symptoms were alleviated one month after the operation. Conclusion Lower anterior cervical approach combined with presternum-splitting approach for CTJST may provide adequate exposure to the lesion, keep the bone graft with internal fixation and spinal stability, and correct the kyphosis.
Objective To explore the surgical procedure and effectiveness of total spondylectomy and spine reconstruction through posterior approach to treat thoracolumbar vertebra tumor. Methods Between June 2004 and July 2008, 14 cases of thoracolumbar vertebra tumor underwent one-stage total spondylectomy through posterior approach and spine reconstruction with posterior pedicle screw system and bone graft. There were 11 males and 3 females with a mean age of 47.2 years (range, 36-60 years). The disease duration was 3-15 months. Affected segments included T3 in 1 case, T4 in 3 cases, T8 in 3 cases, T9 in 2 cases, T10 in 3 cases, T12 in 1 case, and L1 in 1 case. The postoperative pathological results were 3 cases of bony giant cell tumor, 1 case of osteoblastoma, 2 cases of osteosarcoma, and 8 cases of metastatic tumor. According to Tomita et al. grading system, there were 1 case of type II, 5 cases of type III, 3 cases of type IV, and 5 cases of type V. According to Frankel classification of preoperative spinal cord function, 3 cases were rated as grade B, 4 as grade C, 5 as grade D, and 2 as grade E. Results Wound heal ing by first intention was obtained in all cases, and no blood vessel and nerve injury occurred. Fourteen patients were followed up 11-64 months (mean, 32.5 months). The local pain was rel ieved significantly. At 6-8 months after operation, the X-ray films and CT showed that bone graft fusion at Bridwell I grade was achieved. At 10 months, the postoperative spinal cord function was improved from grade B to grade D in 2 cases, from grade C to grade D in 1 case, and the other 9 cases reached grade E. The patients had normal walking function. Two patients died of l iver metastasis and brain metastasis at 11 and 15 months postoperatively, respectively; 1 patient with osteoscarcoma died of lung metastasis at 16 months; and 1 case of osteoscarcoma developed local recurrence at 8 months postoperatively. Internal fixation was rel iable without loosening and breakage and the spine was stable. Conclusion Total spondylectomy and spine reconstruction through posterior approach is an effective method with advantages of relative minimal injury, radical tumor excision, low local recurrence, and adequate spinal cord decompression.
【摘要】 目的 探讨经后路全脊截骨联合椎弓根螺钉治疗胸腰椎脊柱后凸畸形的手术评估和临床疗效。 方法 2004年4月－2010年6月采用后路脊椎截骨椎弓根螺钉内固定治疗脊柱后凸畸形15例，其中男11例，女4例；年龄16~61岁，平均49岁。陈旧性胸腰椎骨折后凸10例，结核后凸3例，椎体发育不良2例；后凸顶点：胸9椎体1例，胸11椎体3例，胸12椎体4例，腰1椎体5例，腰2椎体2例。脊柱后凸Cobb角35~61°，平均46°。Frankel分级：E级2例，D级8例，C级4例，B级1例。 结果 术中出血800~1 800 mL，平均1 000 mL；术中1例左侧胸神经根损伤；1例术后双下肢肌力感觉减退。15例患者均获随访，随访时间10~30个月，平均12个月。术后6个月Cobb角5~10°，平均矫正率86.5%。术后6~10个月X线片显示截骨平面骨性愈合，术后神经功能恢复情况，除1例B级恢复至D级外，其余为E级。内固定物无松动、断裂和纠正度数丢失等并发症。 结论 经后路脊柱截骨联合椎弓根螺钉内固定具有减压、矫形同时进行，矫正度数大，并发症少，临床效果明显。【Abstract】 Objective To explore the surgery assessment and clinical outcome of the treatment for thoracolumbar kyphosis by whole posterior spinal osteotomy combined with pedicle screw. Methods Fifteen patients including 11 males and 4 females with kyphosis were treated by posterior spinal osteotomy combined with pedicle screw from April 2004 to June 2010. The age of them ranged from 16 to 61 years old averaging at 49. There were 10 cases of old thoracolumbar fracture kyphosis, 3 cases of tuberculosis kyphosis, and 2 cases of poor vertebral growth. As for kyphosis vertices, there were 1 case of T9, 3 cases of T11, 4 cases of T12, 5 cases of L1, and 2 cases of L2. Kyphosis Cobb angle ranged from 35° to 61°, averaging at 46°. Based on Franke Grade, there were 2 grade E cases, 8 grade D cases, 4 grade C cases, and 1 grade B case. Results Intraoperative blood loss was from 800 to 1 800 mL with an average of 1 000 mL; There was 1 case of left thoracic nerve root injury during operation and 1 case of lower extremity muscle strength hypoesthesia after operation. All the 15 patients were followed up for 10 to 30 months with an average time of 12 months. Six months after surgery, Cobb angle ranged from 5° to 10°, with an average correction rate of 86.5%. Six to ten months after osteotomy, X ray showed a good bone healing condition. As for the recovery status of neurological function after surgery, All patients recovered to grade E except 1 patient who returned to grade D from grade B. No such complications as fixation without loosening, fracture or loss of correction degree occurred. Conclusion In posterior spinal osteotomy combined with pedicle screw fixation, decompression and correction can be carried out at the same time to correct a large degree of kyphosis with few complications. The clinical effect is obvious.