Bacterial cellulose (BC) is a high-purity nanometer cellulose secreted by some bacteria. Compared with plant cellulose, it possesses an array of unique properties, including high crystallinity, high water content, good biocompatibility, high mechanical strength and an ultra-fine fiber network. BC is prosperous as a new type of biomedical material, which has medical applications such as wound dressing, artificial skin, artificial blood vessels and tissue engineering scaffolds. There are, however, some problems to be solved on the large-scale application of BC, such as the high cost, low yield, and poor mechanical stability and so on.