【摘要】目的探索内镜直视下应用带膜记忆合金支架对晚期食管、贲门恶性狭窄的介入治疗方法。方法2005年1月2009年11月对49例失去手术机会或拒绝手术的晚期食管癌或贲门癌致食管或贲门狭窄患者,行电子胃镜引导下放置镍钛合金支架;对狭窄程度重、胃镜不能通过者,先行Savary探条扩张再放置支架。结果49例均成功置入支架,解除狭窄有效率达100%。结论内镜直视下带膜支架置入操作方法简便、安全,可改善患者的生存质量,延长生存时间。
【摘要】 目的 观察莫沙必利联合复方消化酶胶囊治疗功 能性消化不良的临床疗效和安全性。方法 2008年1月—2009年7月对62例功能 性消化不良患者随机分为两组,每组31例,两组均口服莫沙必利片,三餐饭前30 min服用5 mg;试验组加服复方消化酶胶囊,进餐后30 min服用1粒。4周后观察疗 效。结果 试验组治疗总有效率明显优于对照组,分别为87.1%和61.3%(Plt;0 05)。对上腹痛、餐后饱胀、早饱、上腹烧灼感症状改善情况进行比较,试验 组治疗前后的症状总积分及症状改善有效率与对照组比较差异有统计学意义( Plt;005),而且起效时间明显缩短。两组患者均未发现严重不良反应。结论 莫沙必利联合复方消化酶胶囊治疗功能性消化不良安全有效，其疗效明显优于 单用促动力药莫沙必利。
Objective To compare the clinical efficacy and safety of suturesuspension single hole laparoscopic cholecystectomy and traditional laparoscopic cholecystectomy (LC) in the treatment of gallbladder disease. Methods A total of 86 cases who got treatment in our hospital from February 2014 to July 2015 were collected prospectively, and then 86 cases were divided into 2 groups: 43 cases of control group underwent LC and 43 cases of experimental group underwent suturesuspension single hole laparoscopic cholecystectomy. Clinical efficacy and safety of the two groups were compared. Results ① Complication. No one suffered from bile duct injury, bile leakage, bile duct stricture, and umbilical hernia; but there were 2 cases suffered from complications in control group, including 1 case of abdominal pain and 1 case of bloating, and the morbidity was 4.65% (2/43). The morbidity of experimental group was 0, there was no significant difference between the 2 groups in the morbidity (P>0.05). During the follow-up period, 1 case suffered from long-term compilation in experimental group, and 2 cases in normal group, there was no significant difference in the long-term complication between the 2 groups (P>0.05). ② Operation and hospitalization. The blood loss and operation time in the experimental group were lower than those of the control group (P<0.05), but there was no significant difference in the hospital stay and hospitalization cost between the 2 groups (P>0.05). ③ Postoperative electrolytes, liver and kidney function. The levels of Na+ and K+ in the experimental group were higher than those of the control group (P<0.05), and the levels of alanine aminotransferase and aspartate aminotransferase were lower than those of control group (P<0.01), but there was no significant difference in the blood urea nitrogen and serum creatinine between the 2 groups (P>0.05). ④ The recovery of gastrointestinal function after surgery. The anal exhaust time and bowel sounds recovery time in experimental group were shorter than those of the control group (P<0.01). Conclusion Suturesus-pension single hole laparoscopic cholecystectomy in the treatment of gallbladder disease is safe, effective, and minimally invasive, and it has little disturbance on gastrointestinal function and liver function, which is worthy of clinical application.
Objective To explore the clinical effect of ventricular septal defect repair and lung allograft (simply as "heart repair and lung transplant") in the treatment of ventricular septal defect complicated with severe pulmonary hypertension. Methods A 21-year-old female patient with ventricular septal defect and severe pulmonary hypertension was treated with cardiopulmonary bypass (CPB) under general anesthesia, and then right lung transplantation was performed, and then left lung transplantation was performed after changing body position. Results The operation was conducted successively. The intraoperative CPB support time was 90 minutes, and the blood loss was 2000 mL. Extracorporeal membrane oxygenation was removed on the second day after operation, the ventilator was evacuated on the third day, and the patient recovered and discharged on the 38th day. Postoperative echocardiography showed significant improvement in pulmonary artery pressure. Conclusion For patients with simple congenital heart disease complicated with severe pulmonary hypertension, "heart repair and lung transplant" can improve their quality of life.