【摘要】 目的 探讨胶囊内镜对小肠疾病的诊断价值及顺应性和安全性。 方法 分析2009年4月-2010年3月对35例疑有小肠疾病者行胶囊内镜检查的临床资料。 结果 35例中发现小肠病变26例 （74.3%），包括血管畸形9例，间质瘤1例，息肉2例，小溃疡 1例，非特异性炎症 11例，寄生虫2例，其中 4例患者同时存在两种病变。所获取的图像质量良好。胶囊胃内运行平均时间为 62 min（5～460 min），小肠运行时间为 347 min（103～538 min），平均到达盲肠时间为384 min （120～540 min），平均记录时间为547 min（299～605 min），平均获取照片数为54 766张，胶囊排出体外时间平均为33 h（10～120 h）。受检者顺应性良好，无任何并发症发生。 结论 胶囊内镜是一种对小肠疾病具有较高的检出能力；其安全性高、顺应性好 。【Abstract】 Objective To investigate the diagnostic value of capsule endoscope for small intestine diseases, and to evaluate the compliance and security of capsule endoscopy. Methods The clinical data of 35 patients who underwent capsule endoscopy due to small bowel diseases between April 2009 and March 2010 were retrospectively analyzed. Results In the 35 patients, 26 (74.3%) had intestine diseases including vascular malformation in nine, interstitialoma in one, polyp in two, aphtha in one, non-specific inflammation in 11 and parasite in two; 4 patients had two lesions simultaneously. The quality of the obtained images was good. The average running time of the capsules in the stomach ranged from five to 460 minutes with an average time of 62 minutes. The running time of the capsules in the small intestine ranged from 103 to 538 minutes with an average of 347 minutes. The running time of the capsules arriving at the cecum ranged from 103 to 538 minutes with an average of 347 minutes. The time of the capsules egested out ranged from 10 to 120 hours with an average of 33 hours. The recording time ranged from 299 to 605 minuets with an average of 547 minutes. The mean acquired images were 54 766 pieces, The patients had good compliance, and none had any complications. Conclusion The capsule endoscopy had high security and good compliance. It has high detectivity in diagnosing small intestine diseases.