Objective To investigate patients in gynecological endocrinology clinic with the following three pieces of information: how did they provide their symptom information, how did they understand diagnostic and therapeutic information, and what was their attitude towards the visit, and to get to know about the situation and problems in doctor-patient communication, so as to aim directly at improving the efficiency of diagnosis and treatment. Methods A total of 403 patients, who visited Prof. HAN Zi-yan’s clinic in the hospital from April to August 2010, were evaluated using self-edited Assessment on Doctor-patient Communication in Gynecological Endocrinology Outpatient Clinic. Results a) As to the situation of patients providing symptom information as well as understanding diagnostic and therapeutic information, when doctor asked, only 29% (118/403) of patients could narrate their treatment history clearly, and 38% (152/403) could tell their examination history exactly. After doctors’ explanation, only 21% (86/403) understood their examination results correctly, and 27% (108/403) understood management and therapeutic advice. The result of correlation analysis showed the accuracy of patients in providing disease information and accepting diagnostic and therapeutic information was higher in patients aged from 21 to 40 rather than those younger than 20, in patients well- educated rather than those with little education at the primary school, and in patients who were also engaged in medical work, All differences were significant (all Plt;0.05); and b) As to patients’ attitude towards visit, 55% (222/403) of patients hoped to get more attention from doctor, and 37.5% (151/403) overly expected the visit. Conclusion In the professor’s gynecological endocrinology outpatient clinic, many patients can’t clearly provide their treatment and examination history, neither understand exam situation and therapeutic advice at that visit, which are influenced by their age, education and occupation. In addition, psychological needs of patients should be concerned, too
目的 探讨3种不同助孕方案在≥40岁妇女体外受精-胚胎移植(IVF-ET)周期中的临床效果。 方法 回顾性分析2010年8月-2012年2月期间,于四川大学华西第二医院生殖中心行IVF-ET助孕、年龄≥40岁妇女共245个周期的临床资料,排除一侧卵巢缺如患者3例,余242个周期根据助孕方案不同分为3组:拮抗剂组(GnRH-A方案组)44个周期、长方案组109个周期及短方案组89个周期,比较3种方式助孕的临床效果。 结果 3组均无早发黄体生成素峰;长方案组应用促性腺激素(Gn)的时间最长,应用Gn数量最多,获得最高的获卵数及获胚数(P<0.05);3组的受精率、优胚率、冷冻胚胎数、周期取消率、卵巢过度刺激综合征发生率、早期流产率均无统计学意义(P>0.05),短方案组的种植率及临床妊娠率最低(P<0.05)。 结论 GnRH-a长方案在≥40岁妇女的IVF-ET周期中具有较好的临床结局,在≥40岁妇女IVF-ET周期中具有与长方案相似的结局,并且可以减少Gn使用量,提高卵泡及胚胎质量,短方案组对≥40岁妇女临床效果较差。
目的 探讨妊娠期甲型H1N1流感的临床特点。 方法 对乌鲁木齐市妇幼保健院2009年11月-2010年1月收治的妊娠期甲型H1N1流感临床资料进行回顾性分析。 结果 同期住院非甲流孕产妇1 856例,确诊甲型H1N1流感52例,发病率2.7%。妊娠期甲型H1N1流感的发热时限及不同孕期与病程时限均无相关关系。使用磷酸奥司他韦(达菲)治疗23例,较未使用此药物患者病程显著缩短[(4.79±2.04) d比(7.26±3.77) d,Plt;0.05]。合并肺炎6例,病程较无合并症患者显著延长[(9.83±4.70) d比(5.37±2.54) d,Plt;0.05]。 结论 妊娠期甲型H1N1流感应予以高度重视,在早预防、早诊断及早治疗的基础上,提早预防合并症的发生。明确诊断后及早使用磷酸奥司他韦可缩短疗程。
【摘要】 目的 探讨各种不同体外受精(IVF)助孕方案对子宫腺肌病伴不孕症患者的疗效。 方法 对2006年1月-2009年6月进行IVF助孕治疗的子宫腺肌病伴不孕症患者63例的临床资料进行回顾性分析。根据是否应用长效促性腺激素释放激素激动剂(GnRH-a)及启动促性腺激素(Gn)时间分为超长方案、长效GnRH-a后长或短方案、常规长方案3组,对IVF助孕疗效进行分析。 结果 3种治疗方案的Gn刺激天数、Gn总量、获卵数、不良反应发生率和流产率比较无统计学意义(Pgt;0.05);3种治疗方案的周期取消率为20.0%、7.7%、30.0%,比较有统计学意义(χ2=5.74,Plt;0.05),方案2的周期取消率低于方案1和方案3,有统计学意义(χ2=7.21,Plt;0.05);3种治疗方案的继续妊娠率为23.0%、37.0%、15.3%,有统计学意义(χ2=11.31,Plt;0.05),方案2的继续妊娠率高于方案1和方案3,有统计学意义(χ2=8.52,Plt;0.05)。 结论 与超长方案和常规长方案相比,子宫腺肌病伴不孕症患者采用长效GnRH-a治疗后长方案或短方案行IVF助孕治疗,妊娠率升高,周期取消率降低。【Abstract】 Objective To investigate the effect of different in vitro fertilization (IVF) treatment protocols on infertile women with adenomyosis. Methods Sixty-four infertile women with adenomyosis who had IVF treatment cycles from January 2006 to June 2009 were retrospectively analyzed. According to administration of long course gonadotropin-releasing hormone agonist (GnRH-a) and the start time of gonadotropin (Gn), all participants were divided into three groups: the first group with ultra-long term protocol, the second group with long or short term protocol after administration of long course GnRH-a and the third group with routine long term protocol. Results There were no differences among the three groups with regard to days of Gn administration, amounts of Gn administration, numbers of retrieved oocytes, prevalence of poor response and miscarriage (Pgt;0.05). The cancelation rates of the three groups were 20.0%、7.7% and 30.0% respectively. There were significant differences in cancelation rates among the groups (χ2=5.74, Plt;0.05), and the cancelation rate in the second group was significantly lower than the other groups (χ2=7.21, Plt;0.05). The ongoing pregnancy rates of the groups were 23.0%、37.0% and 15.3% respectively. There were significant differences in ongoing pregnancy rates among three groups (χ2=11.31, Plt;0.05), and the ongoing pregnancy rate in the second group was significantly higher than the other groups (χ2=8.52, Plt;0.05). Conclusion Compared with the ultra-long term and routine long term protocol of IVF treatment in infertile woman with adenomyosis, the ongoing pregnancy rate might be higher and the cancelation rate might be lower in the long or short term protocol after administration of long course GnRH-a.