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find Author "LI Zhaoting." 1 results
  • Expression and Significance of Vascular Endothelial Growth Factor Receptor-3 in Gastric Carcinoma

    ObjectiveTo investigate the relationship between vascular endothelial growth factor receptor-3 (VEGFR-3) and clinical pathology of gastric carcinoma(GC).MethodsThe expression of VEGFR-3 in 80 GCs and 20 gastric benign tissues (GBT) was detected by immunohistochemistry(SP), by which the density of lymphatic vessels (DLV) was calculated. ResultsThe DLV in GC was (5.800 0±2.318 9)/×200, in GBT (2.380 0±0.462 9)/×200(P=0.000); in GC with lymph node metastasis (6.948 3±1.583 1)/×200, without lymph node metastasis (2.772 7±0.428 9)/×200 (P=0.000). In poorly differentiated type group, DLV was (7.681 8±0.982 9)/×200, higher than that in moderately and highly differentiated type group 〔(3.500 0±1.028 2)/×200, P=0.000〕. DLV in pTNM Ⅰ+Ⅱ was (4.291 7±1.688 0)/×200, in Ⅲ+Ⅳ (8.062 5±0.759 4)/×200 (P=0.000).ConclusionDLV shows positive relations with pTNM stage, differentiation and lymph node metastasis of GC.

    Release date:2016-08-28 04:43 Export PDF Favorites Scan
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