ObjectiveTo analyze the research status and summarize research hotspots and development trends of research on artificial intelligence in stomatology. MethodsData retrieved from the Web of Science Core Collection database from inception to 2021 were analyzed by CiteSpace software. ResultsThe number of publications about artificial intelligence in stomatology was rising. The United States ranked first in terms of publications and cooperation capabilities. Apart from comprehensive stomatology journals, the literature was mainly published by specialist journals of oral and maxillofacial surgery, orthodontic and dental radiology. Oral head and neck tumors were the frontier field of artificial intelligence research in stomatology. Artificial intelligence, including deep learning and neural networks, showed the tremendous potential medical value and economic value in assisting in the diagnosis and treatment decisions of oral diseases. ConclusionThe research of artificial intelligence in stomatology has rapidly increased, which is conducive to the development of stomatology in the direction of digitalization, intelligence, and individuation.
ObjectiveThis study aimed to identify independent risk factors for head and neck squamous cell carcinoma (HNSCC) based on the surveillance, epidemiology, and end results (SEER) database and to develop a nomogram model for predicting patient survival outcomes. MethodsPatients diagnosed with HNSCC from 1975 to 2021 were selected from the SEER database. After applying inclusion and exclusion criteria, 2 271 patients were included and randomly divided into a training cohort and a validation cohort in a 7:3 ratio. Independent prognostic factors were identified using LASSO regression, Cox regression analysis, and the Akaike information criterion (AIC). A nomogram model was constructed, and its discrimination and calibration were assessed using the concordance index (C-index), time-dependent area under the curve (time-dependent AUC), and calibration curves. The nomogram model was compared with the American Joint Committee on Cancer (AJCC) staging system using decision curve analysis (DCA), net reclassification index (NRI), and integrated discrimination improvement (IDI) to evaluate clinical utility and risk stratification performance. ResultsFive independent prognostic factors (age, marital status, N stage, tumor stage, and radiotherapy) were selected to build the nomogram model for HNSCC. The C-index values of the model were 0.731 4 (95%CI 0.714 5 to 0.748 5) in the training cohort and 0.735 1 (95%CI 0.709 1 to 0.761 0) in the validation cohort. The time-dependent AUC values were all above 0.7, indicating good discriminatory ability. Moreover, decision curve analysis showed that the nomogram model provided higher clinical net benefits at different threshold probabilities and performed better than the AJCC staging system in identifying high-risk patients. ConclusionThis study develops a nomogram model based on the SEER database to predict survival outcomes in patients with HNSCC. The model demonstrates high discrimination and clinical utility, offering a personalized prognostic tool for clinicians.
ObjectiveTo analyze the hotspots and frontiers of oral lichen planus research by bibliometric methods.MethodsWe searched Web of Science Core Collection database to obtain studies on oral lichen planus from inception to January 1st, 2020. After data extraction, Excel 2016 and CiteSpace software were used to carry out descriptive and visual analysis.ResultsA total of 3 105 articles and reviews were included, and the annual publication volume showed a steady growth trend. The research hotspot terms of oral lichen planus were cancer, lesion, and management of the disease. Moreover, pathogenesis, potentially malignant disorder, classification, and diagnosis were defined as novel research frontiers.ConclusionsThrough the bibliometric method, the research hotspots and frontiers of oral lichen planus are displayed intuitively, which provides references for future research.