ObjectiveTo evaluate the effect of surgical treatment of vertebral artery stenosis and to summarize the experience.MethodThe clinical data of 6 patients undergoing surgical treatment from September 2018 to September 2019 were retrospectively analyzed.ResultsAll the procedures were successfully performed without intraoperative cerebral infarction, injury of thoracic duct or nerve disconnection by mistake. The operative time was 120 to 270 minutes, the median was 180 minutes. The blood loss was 50 to 150 milliliters, and the median was 65 milliliters. One patient suffered from Horner’s syndrome after the operation. One patient suffered from cerebral infarction on 4 days after the operation. During the follow-up of 3–10 months, three patients felt dizziness relieved and there were no anastomotic stricture or new cerebral infarction happened.ConclusionsSurgical treatment is safeand effective for vertebral artery stenosis. Revascularization of the carotid and vertebral arteries at the same time shouldbe avoided.