To investigate the method and cl inical effect of double-plating fixation in treatment of distal humerus fractures. Methods From April 2003 to January 2009, 21 patients with distal humerus fracture were treated with l imited contact compression plate and reconstruction plate via posterior elbow incision and approach inside and outside the edge of both sides of the triceps. There were 12 males and 9 females, aged from 20 to 63 years (39 years on average). The causes of injury were fall ing in 13 cases, traffic accident in 6 cases, and fall ing from height in 2 cases. According to the classification of Association for the Study of Internal Fixation (AO/ASIF), 8 cases were classified as type 12-B1, 2 as type 12-B2, 7 as type12-B3, 3 as type 13-A2, and 1 as type 13-A3. The course of disease averaged 4.8 days. Results Secretion was observed at incision in 1 case 2 weeks after operation, and incision healed after dressing change; other incisions healed by first intention. Transient numbness of ring and l ittle fingers occurred in 2 cases 2 days after operation; no iatrogenic nerve paralysis occurred. All patients were followed up 13 to 18 months (15 months on average). The X-ray films showed bone healed 6 months after operation. No postoperative joint adhesion occurred, and the motion of elbow joint ranged from 0° to 135°. According to Morrey evaluation standard, the results were excellent in 17 cases, good in 2 cases, and fair in 2 case; the excellent and good rate was 90.5%. Conclusion Double-plating fixation has the advantages of wide indications, rigid internal fixation, and significant curative effects in treatment of distal humerus fractures.
ObjectiveTo evaluate the diagnostic value of BRAFV600E mutation test in high-risk thyroid nodules with easily underdiagnosed fine-needle aspiration biopsy (FNAB) results.MethodsRetrospectively collected 122 cases of thyroid nodule who treated in the Hebei Petrochina Central Hospital between January 2017 and December 2018, all the cases admitted preoperative ultrasound and FNAB detection. All of the patients had the non-positive cytological results of FNAB and the high-risk features of ultrasound. Contrasted the postoperative pathological coincidence rate of combination of FNAB and BRAFV600E test with FNAB alone.ResultsThe BRAFV600E mutation rate was 27.0% (33/122). The positive rate of BRAFV600E mutation increased with the increase of ultrasound thyroid imaging reporting and data system(TI-RADS) grade (P<0.05), which was independent of patients’ age, gender, number of nodules, diameter of nodules, and FNAB results (P>0.05). The coincidence rate of FNAB combined with BRAFV600E mutation detection was higher than that of FNAB alone ［86.9% (106/122) vs. 69.7% (85/122), P<0.05).ConclusionsThe BRAFV600E mutation test can detect papillary thyroid carcinoma that might be missed by FNAB. We recommend that FNAB should be routinely accompanied by the BRAFV600E mutation test in the high-risk thyroid nodules.