【摘要】 目的 评估乳酸清除率与重症创伤患者预后的关系。 方法 回顾性分析2010年1-6月收住曲靖市第一人民医院ICU科的37例重症创伤患者的初始血乳酸值、第2次血乳酸值、乳酸清除率及患者的预后,将患者分为存活组和死亡组,比较两组患者初始血乳酸值、乳酸清除率的差异。 结果 两组患者年龄、性别、初始血乳酸值差异无统计学意义(Pgt;0.05)。存活组血乳酸清除率(48.26±21.57)%明显高于死亡组(11.71±20.88)%,差异有统计学意义(Plt;0.001);当乳酸清除率≥13%时,能较好地预测患者生存,其灵敏度为96%,特异度为80%。 结论 乳酸清除率可用于评估重症创伤患者的预后。【Abstract】 Objective To evaluate the correlation between prognosis and lactate clearance in severe trauma. Methods The clinical data of 37 patients with severe trauma admitted between January and June 2010 in the First People′s Hospital of Qujin were analyzed retrospectively. These data included initial blood lactate concentration, second blood lactate concentration, lactate clearance rate, and prognosis of the patients. The patients were divided into survivor group and non-survivor group, and the differences of initial blood lactate concentration and lactate clearance rate between them were compared. Results There were no differences in age, sex, and the initial blood lactate concentration (Pgt;0.05) between the two groups. Compared with non-survivors, the survivors had a significantly higher lactate clearance [(48.26±21.57)% vs. (11.71±20.88)%, Plt;0.001]. Patients with a lactate clearance higher than or equal to 13% had a sensitivity of 96%, specificity of 80%, for predicting survival. Conclusion Lactate clearance rate can be used to predict the prognosis of severe trauma.