ObjectiveTo explore the effect of lidocaine on postoperative pain management after throat surgery. MethodsSixty patients undergoing throat surgery between June 2011 and May 2013 were randomly divided into trial group and control group, with 30 in each group. Patients in the trial group accepted lidocaine for pain management, while the control group used dicaine. Pain management effect was observed and compared between the two groups. ResultsThe pain scores of patients at hour 0.5, 2.0, 6.0, and 24.0 after surgery were 2.7±0.8, 2.2±0.9, 1.7±0.8, and 1.5±0.3 in the trial group, and 4.7±1.1, 4.2±0.8, 3.4±0.7, and 2.9±0.5 in the control group, and the differences were significant (P<0.05). Postoperative incidences 6.7% in the trial group, and 30.0% in the control group, and the difference was also significant (P<0.05). ConclusionLidocaine can reduce the pain of patients in postoperative pain management after throat surgery, with such advantages as long-time functioning, no toxic side effect, and obvious effect, which is worth promoting.
ObjectiveTo know the status and risk factors of occupational exposure in a top-class hospital in Sichuan, and provide the basis for occupational safety and protective measures. Methods"Hospital Medical Staff Occupational Exposure Registration Form" was used in this retrospective study. Statistical analysis was performed on medical workers' exposure data between January 2011 and June 2014 in a top-class hospital in Sichuan Province. ResultsA total of 139 cases of occupational exposures were recorded in some of the medical staff. There were more females than males. Nurses had the most exposures (70.5%), and the exposure sources were mainly human immunodeficiency virus and hepatitis B virus (27.9% and 21.0%, respectively). The exposure type was mainly sharp injury (84.2%). Exposure occurred mainly in surgery (47.5%), and different job or places had different exposure types with significant differences (χ2=12.683, 20.897, P<0.05). Sharp injury was mainly caused by the scalp needle and syringe, and the injured sites were mainly upper limbs (98.3%). However, exposure to blood and body fluids occurred mainly on upper limbs (54.5%) or face (45.5%). ConclusionOccupational exposures are mainly sharp injuries, especially in surgeries. Women, nurses or medical staff with low qualifications had the highest exposure risk. Thus, occupational safety and protection training should be strengthened.
ObjectiveTo systematically evaluate the efficacy of probiotics in preventing antibiotic-associated diarrhea (AAD) in aged people. MethodsPubMed, Web of Science, the Cochrane Database of Systematic Reviews, the Cochrane Controlled Trials Register, CNKI, VIP, and WANFANG electronic databases were searched for studies published, and references of included studies and reviews were screened from database inception to April 2014. Only randomized, controlled trials involving patients older than 65 years were included. Furthermore, only the trials which combined antibiotic administration and probiotic therapy for the prevention of AAD and Jadad score >3 were extracted. ResultsA total of eight articles containing 3 680 subjects (1 843 in the probiotic group, 1 837 people in the control group) met the inclusion criteria. Meta-analysis showed that there was no significant difference in the risk of antibiotic-associated diarrhea (AAD) between probiotics and control groups[RR=0.76, 95%CI (0.51, 1.13), P=0.17]. Further subgroup analysis found that compared with the control group, saccharomyces[RR=1.24, 95%CI (0.70, 2.19), P=0.46], lactobacillus[RR=0.59, 95%CI (0.31, 1.13), P=0.11], multi-probiotics combination[RR=0.58, 95%CI (0.24, 1.41), P=0.23] in the probiotics group were not significantly different. ConclusionThere is no evidence to support that probiotics can reduce the risk of AAD among aged people administrated with antibiotics therapy.