ObjectiveTo investigate the effect of distortion product otoacoustic emission (DPOAE) in hearing assessment for children with mumps, by comparing the results of DPOAE and auditory brainstem response (ABR) threshold value examination. MethodsA total of 116 children (232 ears) with mumps and 50 healthy children (100 ears) without mumps received DPOAE and ABR threshold value examination between March 2010 and October 2012. The results of these two examinations were compared in the first place. Then, The passing rate of DPOAE and the normal rate of ABR were compared between the two groups. ResultsThe passing rate in the mumps group was significantly lower than that in the control group[94.83% (220/232), 100.00% (232/232); P<0.05]. The pure tone test of 6 children (12 ears) in the mumps group who did not pass the DPOAE screening test showed that they had slight or moderate hearing loss. The ABR hearing thresholds of all children were normal. No significant difference was detected in Ⅲ wave latency, Ⅰ-Ⅲ and Ⅲ-Ⅴ intervals based on 75 dB nHL (P>0.05). However, there was a significant difference in the latency of I wave, V wave and interval between Ⅰ and Ⅴ between the two groups (P<0.05). The normal rate of ABR was significantly higher than the passing rate of DPOAE in the mumps group (P<0.05). ConclusionThe hearing is normal in all mumps children. However, mumps virus infection can affect the function of the eighth nerve and some auditory nuclei in the brainstem. Although DPOAE can be a useful method for hearing assessment in the mumps children, other hearing tests including ABR should also be considered.
Objective To investigate the protective effect of autologous platelet separation on blood in surgery for Standford type A aortic dissection. Methods A total of 180 patients with Standford type A aortic dissection undergoing elective major vascular surgery in our hospital from July 2014 to March 2016 were enrolled. There were 123 males and 57 females with age ranging from 19 to 68 years and weight of 50-85 kg. The patients were randomly divided into two groups. Patients in group A (n=92, 65 males, 27 females, mean age of 45±21 years) received intraoperative autologous blood recovery; while those in group B (n=88, 58 males, 30 females, mean age of 43±24 years) received autologous platelet rich plasma (APRP) and intraoperative autologous blood recovery. The whole process of platelet separation was completed before heparinization. The relevant indicators of blood coagulation function before the induction of anesthesia (T1), before heparinization (T2), immediately postoperatively (T3) and 1 h (T4), 24 h (T5) postoperatively were measured. Cardiopulmonary bypass, aortic cross-clamping time, drainage volume at postoperative 1 h, 24 h and allogeneic blood transfusion volume were recorded. Results The whole blood volume of group B in the platelet separation in emergency was 1 305±110 ml, and collected platelet rich plasma was 275±30 ml, platelet counts (630±220)×109/L, accounting for 25%±5% of platelets of whole blood, and platelet separation time was 32±9 min. Compared with group A, platelet count at postoperative 1 h in group B was significantly higher; drainage volume at postoperative 1 h, 24 h, allogeneic red blood cells, plasma transfusion volume and allogeneic platelet infusion rate decreased significantly (P<0.05). Group B had less postoperative complications (P<0.05). Conclusion Preoperative autologous plateletpheresis combined with intraoperative autologous blood recovery can significantly improve the coagulation function of patients with vascular surgery, and reduce the amount of allogeneic blood transfusion and postoperative bleeding.