Objective To demonstrate the importance of bioreactor to tissue engineering and to disscuss the direction of bioreactor- researching. Methods Alarge quantity of literature was reviewed, analyzed and summarized. Results Bioreactor has greatly promoted the progress of tissue engineering in heoretics and practice,and has become one of the most important parts of tissue engineering. Conclusion Bioreactor is indispensable for tissue engineering,and it should be developed along integration,automation and intelligentificaton.Its application should run through the whole process of tissue engineering.