Objective To investigate and analyze the employment status and related influencing factors of maintenance hemodialysis (MHD) patients. Methods MHD patients from four hemodialysis centers in Beijing between January 2020 and January 2021 were selected. The baseline data and clinical data of patients with long dialysis interval were collected. An anxiety and depression survey was conducted on the patient. Results A total of 108 MHD patients were included. Among them, 41 patients were working and 67 patients were not working. Among the 41 patients at work, there were 3 workers, 1 farmer, 14 company employees, 6 public institution employees, 11 self-employed, 5 freelancer and 1 other. Among the 67 patients who did not work, 8 patients had the ability to work but did not work. Body mass index was an independent influencing factor for employment in MHD patients [odds ratio=1.135, 95% confidence interval (1.017, 1.266), P=0.024]. Conclusion The nutritional status of MHD patients should be taken seriously to improve their employment rate.
ObjectiveTo investigate the effect of 24-week intradialytic progressive resistance exercise on hemoglobin and iron metabolism in maintenance hemodialysis (MHD) patients.MethodsFrom April to May 2019, 62 MHD patients were enrolled and randomly assigned into exercise group (n=31) and control group (n=31). Both groups of patients received regular routine hemodialysis, on that basis, patients in the exercise group completed intradialytic resistance exercise three times per week for 24 weeks. Each exercise included 8-10 muscle groups (grasping the grip ring with both hands, flexion and extension of the elbows and shoulders on the non-vascular side and lower limbs with sandbag), 3 sets of 15 repetitions with a rest of 1-2 min between 2 sets. Exercise began with a low load, the sandbag weight was gradually increased, and the Borg score was aimed to be 11-13 points after exercise. Hemoglobin, serum ferritin, transferrin saturation, serum creatinine, high-sensitivity C-reactive protein, urea clearance index, recombinant human erythropoietin (rHuEPO) dosage at baseline and after 24 weeks, as well as the cumulative iron supplement dose and hemoglobin variation of the two groups during the study period were evaluated.ResultsThere were 20 patients in the exercise group and 30 ones in the control group who completed the study. After 24 weeks of progressive resistance exercise, the medium (lower quartile, upper quartile) of the amount of rHuEPO in the exercise group decreased from 6 000 (6 000, 9 000) U/week to 6 000 (4 500, 7 125) U/week (Z=−2.599, P=0.009), while that in the control group had no statistically significant difference (Z=−1.340, P=0.180); there was no statistically difference in hemoglobin, hemoglobin coefficient of variation, serum ferritin, transferrin saturation, or 24-week cumulative iron supplementation between the two groups.ConclusionIntradialytic progressive resistance exercise can reduce the amount of rHuEPO in MHD patients, which is benefitial to optimizing the management of hemoglobin.