ObjectiveTo evaluate the value of real-time indocyanine green fluorescence imaging navigation (ICG-FIN) in laparoscopic rectal cancer surgery. MethodsThe patients who adopted ICG-FIN during laparoscopic rectal cancer surgery in the Department of Anorectal Surgery of Xuzhou Central Hospital from April 2022 to June 2023 according to the inclusion and exclusion criteria (ICG-FIN group) were collected, meanwhile matching (1∶1) of patients who did not adopt ICG-FIN during laparoscopic surgery from January 2021 to May 2022 (control group). The general data, surgical conditions, intraoperative and postoperative outcomes between the two groups were compared. ResultsThere were 62 patients in the ICG-FIN group and 62 patients in the control group. There were no statistical differences in the gender, age, body mass index, comorbidities, and so on between the two groups (P>0.05). The tumor localization, lymph node tracing, fluorescence imaging of the intended resection of intestinal tract and anastomotic site were observed in the ICG-FIN group. Seven patients (11.3%) had changed in the intended resection of intestinal anastomotic line during surgery, while there were no changes of the surgical plan in the control group. There were no statistical differences (P>0.05) in terms of surgical method, operative time, intraoperative bleeding, proportion of ileostomy, time of the first postoperative exhaust, postoperative hospital stay, and incidence of short-term complications between the two groups. Compared with the control group, the incidence of anastomotic leakage was lower (P=0.012), and the number of lymph nodes cleaned was more (P=0.016) in the ICG-FIN group. However, there was no statistical difference in the number of positive lymph nodes detected between the two groups (P=0.343). ConclusionsAccording to the results of this study, ICG-FIN is a reliable and effective method during laparoscopic rectal cancer surgery, which can accurately localize tumor, trace and guide lymph node dissection. Real-time evaluation of intestinal blood flow perfusion is of great practical value in reducing anastomotic leakage.
Objective To visually present the related research progress, hot spots, frontiers, and trends of Guizhi Shaoyao Zhimu decoction (GSZD) in China in the recent 11 years, aiming at better guiding related clinical research. Methods The published GSZD-related articles were searched in China National Knowledge Infrastructure, Wanfang Database, Wanfang Medical Network, and VIP Chinese Journals Service Platform, and the time limit was from January 1st, 2012 to December 8th, 2022. After screening, CiteSpace 6.1.R3 software was used to visually analyze the included documents. Results A total of 1791 articles were retrieved, and 595 articles were included after screening. The number of papers published in the year showed a fluctuating upward trend. The included articles were from 179 journals and 21 universities and research institutes, among which 12 institutions (including 11 journals) published more than or equal to 10 articles, the cumulative number of articles published by these 12 institutions accounted for 27.23% of the total number of articles published, and Journal of Rheumatology and Arthritis published the most papers (22 articles). The main author teams in this field were Gao Yongxiang, Liu Zhenli, and Fang Shubiao. Through keyword analysis, 8 co-occurrence keywords, 10 clustering modules, and 25 emergent keywords were formed. Conclusions In the future, GSZD-related research will continue to grow, and it has great development potential. Research teams should closely cooperate strengthen exchanges, and develop their potential under the guidance of the idea of integrating traditional Chinese and Western medicine, to help it develop better and better serve clinical applications.