ObjectiveTo explore the feasibility and significance of self-training system for oncology nurses by observing the effect of the training in primary hospitals. MethodsFrom January 2013 to January 2015, a cohort of nurses from a primary oncology hospital were trained based on the practical needs of oncologists, nurses and patients.The training system included nursing measures for chemotherapy drug extravasation and other adverse reactions, tumor emergency, peripherally inserted central catheter catheterization, cancer patients' psychological state, rehabilitation of cancer patients and cancer pain.Training and assessment were conducted using a method of combination of theory and practice. ResultsA total of 240 nurses were trained.The theory score before and after training was respectively 72.28±2.56 and 84.85±4.17;the practice score was respectively 63.39±1.42 and 72.68±2.63.There were significant differences between the pre-training and post-training results of theory and practice scores (P < 0.05).The adverse nursing events rate three months before training was 22.1%, and was 8.8% three months after training, and the difference was significant (P < 0.05).The satisfaction rate increased from 59% one month before training to 84% one month after training. ConclusionThe self-training system in primary tumor hospitals can improve the level of nursing care for oncology nurses and is worthy of promotion.