Shortly after the Wenchuan earthquake, we established headquarter of crisis intervention, which was responsible for reporting earthquake situation and training personnel to carry out psychological intervention and publicize earthquake-related knowledge. Then, urgent psychological intervention was provided to the target populations. We offered crisis intervention more than 100 times (40,000 person-times), provided individualized psychological services or therapies over 3,000 person-times and treated more than 200 patients with posttraumatic stress disorder. Meanwhile, we established relevant administration systems including registration, reporting, rapid screening and personnel work logs. Our preliminary survey conducted 1 month after the earthquake showed that the prevalence of posttraumatic stress disorder reached 43%. After the earthquake, the victims’ emotions of depression and anxiety were raised and the prevalence of posttraumatic stress disorder had a sharp increase. The victims’ requirements for psychological crisis intervention after earthquake were immense.