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find Keyword "Reinnervation" 7 results
  • REINNERVATION AFTER ECTOPIC TRANSPLANTATION OF GRACILIS MUSCLE OF RATS

    Objective To study the method of reinnervation after ectopic transplantation of the gracilis muscle in rats. Methods Sixty healthy male rats (age, 8 months; weight, 400-500 g) were randomly divided into 3 groups: the control group, the motor reinnervation group, and the sensory reinnervation group. The right gracilis of the rat was cut off, and the muscle was transplanted to the left leg. In the control group, no reinnervation was performed on the obturator nerve; in the sensory reinnervation group, the obturator nerve was coapted with the recipient saphenous nerve; in the motor reinnervation group, the obturator nerve was coapted with the femoral nerve motor branch. After 25 weeks, the weight of the muscle was measured, and the histological examination was performed. Results Atrophy of the gracilis was found to be a dominant effect in the control group, where the weight of the muscle was 204.0±15.3 mg. In the motor reinnervation group, the weight ofthemuscle was 394.8±12.9 mg, and in the sensory reinnervation group, it was 389.2±13.5 mg, with no significant difference between the two groups (P>0.05). The weight of the muscle in the motor reinnervation group and in the sensory reinnervation group was significantly greater than that in the control group (P<0.05).The tissue observation revealed that the nerve axon was diffusedin the motor reinnervated group, with no nerve endplates found. The motor nervereinnervated flaps showed the viable axons out to the motor endplates. The histological examination revealed evidence of reinnervation. Conclusion The motor or sensory nerve anastomosis after the ectopic transplantation of the skeletal muscle can prevent the atrophy of the muscle and restorepart of the nerve function.

    Release date:2016-09-01 09:23 Export PDF Favorites Scan
  • EXPERIMENTAL STUDY ON THE ARTIFICIAL BLADDER REFLEX ARC ESTABLISHED IN THERAPY OF FLACCID BLADDER AFTER SPINAL CORED INJURY

    Objective To establish the artificial bladder reflex arc by the normal body reflex pathway above the horizon of spinal cord injury to reinnervate the flaccid bladder and restore bladder micturition function. Methods An intradural microanastomosis was performed on the L6 ventral root tothe S2 ventral root. After axonal regeneration,the “patellar ligament-spinal cord center-bladder” reflex pathway was reestablished. A longterm function of the reflex arc was observed in the nerve electrophysiological experiment, detrusor electromyography experiment, and urodynamic testing 8 months after anastomosis. Results Trains of the stimuli(200 μV,5 ms) in the left L6 dorsal root and the nerve at the anastomosizedsite resulted in motor evoked potential from the disal to the anastomosized site before and after the spinal cord was destroyed horizontally between S1 and S4 segment levels in 2 Beegle dogs.The figure and amplitude of the evoked potential were similar to those of the control and general stability which showed anoninterventional wave. The urodynamic test revealed a rapid increase of the bladder pressure and a minor increase in the abdominal pressure. This showed that the bladder detrusor mainly resulted in the pressure increase.The bladder pressure increased to 60% of the normal on average compared with the controls when resulted in the left L6 dorsal root and the nerve anastomosized site were stinulated. Conclusion The long-term observation by the nerveelectrophysiological experiment, detrusor electromyography experiment, and urodynamic test indicate that the new artificial reflex arc can be established successfully. The somatic motor axons can regenerate into the parasympathetic endoneurial tubes of the autonomic nerve.

    Release date:2016-09-01 09:26 Export PDF Favorites Scan
  • EXPERIMENTAL STUDY ON DELAYED REINNERVATION OF LARYNGEAL ADDUCTOR AND ABDUCTOR

    To investigate time of delayed reinnervated laryngeal muscle, 15 dogs were divided into two groups. The right recurrent laryngeal nerves of 10 dogs in experimental group were cut, and repaired at 4, 6, 8, 10 and 12 months intervals by transposition of the phrenic nerve to the recurrent laryngeal nerve after cutting and suturing the adductor branch to the main branch of ansa cervicalis. The right recurrent laryngeal nerves of 5 dogs in control group were cut, but did not repair. Laryngoscope, electromyography, contractile tension of laryngeal muscle and histologic studies were performed at six months postoperatively. The results showed that fair recovery of adduction and abduction was noted within ten months interval, and the effect of adduction was better than that of abduction. The effect decreased gradually with the denervated time increased. The conclusion demonstrated that delayed reinnervation of laryngeal muscle should be performed within ten months.

    Release date:2016-09-01 11:07 Export PDF Favorites Scan
  • CLINICAL USE OF TRANSPLANTATION OF FREE MUSCLE GRAFT WITH NEUROVAS CULAR BUNDLE FOR TREATMENT OF LATE FACIAL PARALYSIS

    Using transplantation of free muscle with microneurovascular anastomosis for 46 cases of late facial paralysis, we selected M. latissimus dorsi as neurovascularized muscle bundle graft in 28 of them. This was not only an operation for facial dynamic reconstruction but also a new method for reinnervation of oral and ocular sphincter. After operation all of them revealed symmetry with voluntary motions. The results were satisfactory. The indications for surgical treatment, the procedure, and the management after the treatment were discussed in details. The importance of reeducation of the regenerating nerve and the necessity of twostaged operation were also discussed.

    Release date:2016-09-01 11:13 Export PDF Favorites Scan
  • ABSTRACTS CLINICAL USE OF IMPLANTATION OF MUSCLE BUNDLE WITH NEUROVASCULAR PEDICLE IN THE TREAMENT OF PARALYSED MUSELE

    On the basis of laboratory research of the reinnervation of poralyysed musele by implanting muscle bundies with neurovascular pedicle ( NVMBI),this method was applied clinically to trcat paralysed musele on extremities and trunks with quite satisfactory result.Detail description of preoperative exammation,operation design,surgical procedure and potoperative management were presented。the mechanism and reason of the good result were dscussed. The anatomical characteristics of the NVMBI we...

    Release date:2016-09-01 11:18 Export PDF Favorites Scan
  • STUDY ON CONTRACTILE PROPERTIES OF THE POSTEROIR CRICOARYTENOID MUSCLE REINNERVATED FROM PHRENIC NERVE

    The contractile function of the posteroir cricoarytenoid muscle was investisated after reinnervated from the phrenic nerve. The data showed that the posteroir cricoarytenoid muscles reinnervated from the phrenic nerve repined contraction very well. As to the contractile properties, it had no difference in the contractile tension and the time of contraction of the posteroir cricoarytenoid muscles on the reinnervated side and on the normal side. The results demonstrate that the method to reinnervate the posteroir cricoarytenoid muscle by the phrenic nerve in order to restore muscle function was possible.

    Release date:2016-09-01 11:34 Export PDF Favorites Scan
  • A FURTHER EXPERIMENTAL STUDY OF MUSCLE BUNDLE WITH NEUROVASCULAR PEDICLE ON REINNERVATION OF PARALYZED MUSCLES

    The model of the denervated lateral head of gastrocnemius musde was adopted in this experiment on 50 rabbits. At random, the denervated muscle on oneside received the soleus muscle bundles with neurovascular pediele implantation (MBNPI). While the other side received the direct soleus nerve implantation (DNI). Eighteen weeks later after the two types of implantations the electromyography, force of muscles, histochmical findings and the electronic microscopic examination of the dernervated muscles of the two...

    Release date:2016-09-01 11:38 Export PDF Favorites Scan
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