Abstract： Quality of life （QOL） refers to an individual’s perception and subjective evaluation of their health and well-being, and has become an important index to evaluate the outcomes of clinical treatment in the last past decades. There are a large number of different instruments to evaluate QOL, and the 36-Item Short Form Health Survey （SF-36） is currently one of the most widely used instruments. In recent years, SF-36 has been used to evaluate QOL of valvular heart disease patients to investigate the risk factors those influence their postoperative QOL, provide more preoperative evaluation tools for clinical physicians, and improve postoperative outcomes of patients with valvular heart disease. However, it is now just the beginning to use SF-36 to examine QOL of valvular heart disease patients. Because of significant differences in sample size, follow-up period, country and culture, current research has some controversial results. This review focuses on the progress in evaluating QOL in postoperative patients with valvular heart disease using SF-36.
Objective To compare the application effects of three psychometric instruments including SF-36, FLIC and QOL-LC in measuring the quality of life of patients with liver cancer. Methods A total of 105 in-patients with liver cancer selected from 2010 to 2011 were included. The quality of life was measured by FLIC, SF-36 and QOL-LC, respectively, and the reliability, validity and responsiveness were calculated and analyzed. Results The reliability and validity of QOL-LC were better than those of SF-36 and FLIC. Both QOL-LC and FLIC showed significant differences in responsiveness based on the changes of physical function and overall quality of life (QOL-LC: t=5.08, P=0.000, t=3.16, P=0.002; FLIC: t=4.02, P=0.000, t=2.21, P=0.030). Except for general health and mental health, the other domains of SF-36 showed significant differences in changes after treatment (physical function: t=5.94, P=0.000; physical role: t=3.07, P=0.003; body pain: t=3.21, P=0.002; vitality: t=3.22, P=0.002; social role: t=2.60, P=0.012; emotional role: t=3.28, P=0.002). Conclusion QOL-LC is a specific scale for liver cancer, and it should be used preferentially. SF-36 and FLIC can measure the general state of quality of life and can be used in patients with liver cancer when specific scale is not available.
Objective To explore the effects on quality of life (QOL), the targeted rates of metabolic parameters and cost-effectiveness in newly diagnosed type 2 diabetic patients who underwent multifactorial intensive intervention. Methods One hundred and twenty seven cases in an intensive intervention and 125 cases in a conventional intervention group were investigated by using the SF-36 questionnaire. The comparison of QOL and the targeted rates of metabolic parameters between the two groups were made. We assessed the influence factors of QOL by stepwise regression analysis and evaluated the efficiency by pharmacoeconomic cost-effectiveness analysis. Results The targeted rates of blood glucose, blood lipid and blood pressure with intensive policies were significantly higher than those with conventional policy (P＜0.05). The intensive group’s role limitations due to physical problems (RP), general health (GH), vitality (VT), role limitation due to emotional problems (RE) and total scores after 6 months intervention were significantly higher than those of baseline (P＜0.05). The vitality scores and health transition (HT) of the intensive group were better than those of the conventional group after 6 months intervention. But the QOL scores of the conventional group were not improved after intervention. The difference of QOL’s total scores after intervention was related to that of HbA1c. The total cost-effectiveness rate of blood glucose, blood lipid, blood pressure control and the total cost-effectiveness rate of QOL with intensive policy were higher than those with the conventional policy. Conclusions Quality of life and the targeted rates of blood glucose, blood lipid and blood pressure in newly diagnosed type 2 diabetic patients with multifactorial intensive intervention policy are better and more economic than those with conventional policy.
ObjectiveTo investigate the reliability and validity of Short-Form 36 Health Survey Scale (SF-36) for evaluating quality of life (QOL) of thoracic surgery patients in a specific regional medical center,and improve care and nursing plan for these patients. MethodsNinety-five patients who were admitted in Department of Thoracic Surgery of West China Hospital from March to May 2012 were enrolled in this study. Ninety-four patients finished a valid questionnaire study including 68 male and 26 female patients with their average age of 62.0±13.0 years. Preoperative diagnosis was squamous cell lung cancer in 8 patients,lung adenocarcinoma in 6 patients,small cell lung cancer in 1 patient,esophageal cancer in 12 patients and undefined lung mass in 67 patients. Postoperative diagnosis was squamous cell lung cancer in 39 patients, lung adenocarcinoma in 28 patients,small cell lung cancer in 8 patients,esophageal cancer in 12 patients,pulmonary tuberculosis in 3 patients and inflammatory pseudo-tumor in 4 patients. Chinese edition of SF-36 was used to evaluate patients' QOL. Cronbach's coefficients (α) and split-half reliability were used to assess its reliability. Its validity was assessed through factor analysis. ResultsCronbach's coefficients (α) of SF-36 were as followed:Physical Functioning (PF) 0.721,Role-Physical (RP) 0.859,General Health (GH) 0.721,Vitality (VT) 0.899,Social Functioning (SF) 0.852,Role-Emotional (RE) 0.872,and Mental Health (MH) 0.598. Split-half reliability of each part was PF 0.725,RP 0.784,GH 0.758,VT 0.749,SF 0.745,RE 0.740,and MH 0.426. Nine principal components were extracted by factor analysis and generally reflected the 8 dimensions of SF-36,which was correspondent to the SF-36 structure. ConclusionSF-36 scale can be used to measure QOL of thoracic surgery patients with good reliability and validity.
Objective To compare the quality of life after laparoscopic and open surgery for gastric stromal tumor patients. Methods We collected the data of the patients undergoing the gastric stromal tumor surgery from May 2011 to August 2016 in West China Hospital of Sichuan University, and compared the basic data, complications, micturition time, hospital stay time, bleeding volume and hospitalization expenses. SF-36 scale was used to evaluate the quality of life. Then, SPSS 19.0 software was used for data analysis. Results Eighty nine patients involving 31 laparoscopic patients and 58 open surgery patients were included. There was no statistical significance in basic line between two groups. The laparoscopic group had shorter micturition time and hospital stay time, less intraoperative bleeding and lower hospitalization costs, the differences between two groups were statistically significant (P<0.05). But there were no significant differences between two groups in the operation time and postoperative complication rate. The SF-36 quality of life scale of laparoscopic group and open surgery group were 737.7±68.3 and 665.1±138.1, respectively. The laparoscopic surgery group had higher scores in validity (VT), social function (SF) and mental health (MH) than those in open surgery group with significant differences (P<0.05). Conclusion Laparoscopic surgery is safe and effective for the patients with stromal tumor. Patients in laparoscopic group have shorter recovery time and higher quality of life than open surgery group. Due to the limited of study design, more high quality studies are needed to verify above conclusion.
ObjectiveTo compare and analyze the postoperative quality of life in patients after minimally invasive coronary artery bypass grafting (MICABG) and conventional median thoracotomy off-pump coronary artery bypass grafting surgery (OPCABG). MethodsFrom November 2015 to January 2018, 94 patients who underwent MICABG in the Peking University Third Hospital were included in the MICABG group. During the same period 441 patients who received OPCABG were included in the OPCABG group. The patients were matched by using propensity score matching method with a ratio of 1∶1. The quality of life was compared between two groups at 1 month, 6 months and 12 months after the surgery using SF-36 scale. ResultsA total of 82 patients were matched for each group. In the MICABG group, there were 66 males and 16 females with a mean age of 62.6±8.2 years. In the OPCABG group, there were 67 males and 15 females with a mean age of 63.2±13.2 years. One month after the operation, the physical health assessment (PCS) and mental health assessment (MCS) of the MICABG group were higher than those of the OPCABG group (50.3±10.6 points vs. 46.1±10.3 points, P=0.011; 59.5±9.3 points vs. 54.2±11.0 points, P=0.002). Scores of these following five dimensions: general health, physical functioning (PF), role-physical, social functioning (SF), role-emotion in the MICABG group were higher than those in the OPCABG group, while the score of body pain was inferior to that in the OPCABG group, and the differences were statistically significant (P<0.05). Six months after the surgery, the PCS and MCS of the two groups were not statistically different (80.0±13.1 points vs. 77.8±12.4 points, P=0.271; 81.6±13.5 points vs. 80.4±11.2 points, P=0.537). However, the scores of PF and SF in the MICABG group were still higher than those in the OPCABG group (P<0.05). Twelve months after the surgery, there was no statistical difference in the score of each dimension between the two groups (P>0.05). ConclusionThe improvement of quality of life within 6 months after MICABG is better than that of OPCABG, and it is similar between the two groups at 12 months after the surgery, indicating that MICABG has a certain effect of improving the short-term quality of life after the surgery, and the long-term quality of life is comparable to conventional surgery.
【摘要】 目的 评价SF-36量表在测量地震伤残人员生存质量中的信度和效度。 方法 利用自填法及访谈相结合的方式调查201例绵竹市某镇地震伤残人员，用重测信度和Cronbach’s α系数分析SF-36信度；因子分析方法分析效度。 结果 SF-36各领域的重测信度分别为:生理功能（PF）0.78、生理问题对功能的限制（RP）0.85、躯体疼痛（BP）0.92、健康总体评价（GH）0.82、活力（VT）0.77、社会功能（SF）0.71、心理问题对功能的限制（RE）0.79、精神健康（MH）0.66；各领域的Cronbach’s α系数分别为:PF 0.89、RP 0.75、BP 0.84、GH 0.86、VT 0.78、SF 0.72、RE0.86、MH 0.50。因子分析共提取了6个主成分，基本反映了量表的8个维度，与量表的结构构思基本相符。 结论 自填法及面对面访谈相结合的方式，将SF-36量表用于该地地震伤残人员生存质量测定具有较好的信度和效度。【Abstract】 Objective To evaluate the validity and reliability of the MOS-36-item Short Form of Health Survey (SF-36) measuring the quality of life (QOL) of disabled people injured in the earthquake. Methods A total of 201 disabled people injured in the earthquake in a town of Mianzhu city were investigated via questionnaire combined with a face-to-face interview. The reliability of the SF-36 was assessed by test-retest reliability and Cronbach’s α coefficient. The validity was assessed through factor analysis. Results The test-retest reliability of the SF-36 included: physical functioning (PF) 0.78, role limitation due to physical problems (RP) 0.85, body pain (BP) 0.92, general health (GH) 0.82, vitality (VT) 0.77, social functioning (SF) 0.71, role limitation due to emotional problems (RE) 0.79, and mental health (MH) 0.66. The Cronbach’s α coefficients were as the follows: PF 0.89, RP 0.75, BP 0.84, GH 0.86, VT 0.78, SF 0.72, RE 0.86, and MH 0.50. Six principal components were extracted by factor analysis and the constructs of the obtained instrument were consistent with the conceived concept in essence. Conclusion The SF-36 survey could measure the QOL in disabled people injured in the earthquake with better reliability and validity by questionnaire combined with a face-to-face interview.