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find Keyword "Seromuscular layer anastomosis" 2 results
  • Randomized Control Study on Seromuscular Layer Anastomosis and Two-Layer Anastomosis in Small Intestinal Suture

    Objective To evaluate the safety and effect of seromuscular layer anastomosis in small intestinal suture. Methods Forty patients with hepatobiliary and pancreatic diseases undergoing biliojejunostomy or cystojejunostomy were randomly divided into seromuscular layer anastomosis group (n=20) and two-layer anastomosis group (n=20) before operation, which received Roux-en-Y end-to-side jejunal seromuscular layer anastomosis and two-layer anastomosis, respectively. Intestinal anastomotic complications and other indexes such as anus venting time were recorded in each group. Results Neither group had intestinal anastomotic complications such as leakage, stricture, obstruction and hemorrhage. Time of venting to normal were (3.6±0.9) d and (3.6±0.8) d in seromuscular layer and two-layer anastomosis group respectively, there was no significant difference between them (Pgt;0.05). Conclusion Seromuscular layer anastomosis is a safe and effective method of small intestinal anastomsis.

    Release date:2016-09-08 10:58 Export PDF Favorites Scan
  • Comparison of Seromuscular Layer Anastomosis, Extramucosal Anastomosis, Single-Layer Anastomosis and Double-Layer Anastomosis of Gastrointestinal Tract in Rabbits

    Objective The effects of seromuscular layer anastomosis, extramucosal anastomosis,single-layer anastomosis and double-layer anastomosis of gastrointestinal tract on anastomotic healing were compared. Methods Chinese rabbits were divided into four groups: group A (double-layer anastomosis, n=10), group B (single-layer inverted anastomosis, n=10), group C (extramucosal anastomosis, n=10) and group D (seromuscular layer anastomosis, n=10). Five anastomoses were performed in each animal: one side-to-side gastroduodenal anastomosis, two end-to-end ileal and colonic anastomoses respectively. Half of each group was sacrificed on postoperative day 3 and 7 respectively to determine in situ anastomostic bursting pressures (ABP) and hydroxyproline (HP) content, and to receive histopathologic examination. Inflammatory index and mucosal healing index of anastomosis were calculated. Results There were no significant differences in case of ABP among the groups on day 3, and with the same result among group A, B and C on day 7 in gastroduodenal, ileoileal and colocolonic anastomoses. On day 7, the ABP of gastroduodenal anastomosis was dramatically higher in group D than group A and B (P<0.05), the ABP of ileoileal anastomosis in group D was significantly increased compared with group A (P<0.01), and the ABP of colocolonic anastomosis in group D was also higher than group A, B and C (P<0.05). There was no statistical difference in HP content among the 4 groups in gastroduodenal and ileal anastomoses on day 3 (Pgt;0.05), and in ileal and colonic anastomoses on day 7 (Pgt;0.05). HP content was higher in group A than group B on day 3 in colonic anastomoses (P<0.05),  and it was also found to be higher in group D than group A on day 7 in gastroduodenal anastomosis (P<0.025). Inflammatory reaction was not different among the 4 groups in gastroduodenal and ileoileal anastomoses on day 3, and the inflammatory indices of gastroduodenal and colocolonic anastomoses in all groups were similar on day 7. The inflammatory index of colocolonic anastomosis was signicantly increased in group A than group C on day 3 (P<0.05), and that of ileoileal anastomosis in group A was higher than group D on day 7 (P<0.05).  The mucosal healing indices of anastomoses were not significantly different among the 4 groups on day 7. Conclusion Seromuscular layer anastomosis of gastrointestinal tract is as safe as other hand-sewn anastomoses, but it is more convenient and simpler than others.

    Release date:2016-09-08 11:49 Export PDF Favorites Scan
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