ObjectiveTo review the current progress of three-dimensional (3-D) printing technique in the clinical practice, its limitations and prospects. MethodsThe recent publications associated with the clinical application of 3-D printing technique in the field of surgery, especially in orthopaedics were extensively reviewed. ResultsCurrently, 3-D printing technique has been applied in orthopaedic surgery to aid diagnosis, make operative plans, and produce personalized prosthesis or implants. Conclusion3-D printing technique is a promising technique in clinical application.