Objective To investigate the relationship between diabetic retinopathy (DR) and coronary atherosclerosis (CAS) in type 2 diabetes patients and other risk factors of DR. Methods A total of 118 patients of type 2 diabetes with DR (DR group), 120 patients of type 2 diabetes without DR matched in age and sex (non-DR group), and 86 normal controls (control group) were enrolled in this study. The body mass index (BMI), blood pressure (BP), fasting blood-glucose (FPG), glycosylated haemoglobin (HbA1C), total cholesterol (TC), triglyceride (TG), high density lipoprotein cholesterol (HDL-C), low density lipoprotein cholesterin (LDL-C), creatinine, estimate glomerular filtration rate (eGFR) and urinary albumin excretion rate(UAER) in all the subjects were measured. Meanwhile, the incidence of CAS in the three groups was detected by 64slice multidetector computed tomography angiography (MDCTA). Assume concurrent DR as dependent variable, clinical indicators and laboratory parameters as independent variable, the risk factors were determined by Logistic regression analysis. In addition, CAS as dependent variable, DR as fixed factor, analysis of covariance was used to investigate the relationship between CAS and DR. Results The incidence of CAS in DR group was higher than that in nonDR group and control group, the differences were statistically significant (chi;2=26.9,35.5;P＜0.05). The results of Logistic regression analysis showed that systolic BP, BMI, CAS, myocardial infarction and UAER were key risk factors for DR ［odds ratio (OR)=1.02, 0.89, 4.50, 3.89, 1.34;P＜0.05］. There was a negative relationship between BMI and DR. The results of analysis of covariance showed that there was significant correlation between CAS and DR (OR=5.31, 95% confidence interval=2.62-10.60; P＜0.05). Conclusion CAS is independently associated with DR in type 2 diabetes patients. In addition, the other risk factors for DR include systolic BP, BMI, myocardial infarction and UAER.
ObjectiveTo investigate the chest radiographic and computed tomographic manifestations of allergic bronchopulmonary aspergillosis (ABPA). MethodWe retrospectively analyzed the chest radiographic and computed tomographic manifestations of 20 ABPA patients treated between December 2005 and December 2013. ResultsChest radiograph showed that there were 4 negative cases, 14 cases of solid mass, 10 cases of increased and disorder of bronchovascular shadows, and 5 cases of bronchiectasis. Chest computed tomography showed that there were one negative case, 18 cases of bronchiectasis, 17 cases of central bronchiectasis among which central and peripheral bronchi were involved in 6 cases and 1 case presented as pure peripheral bronchiectasis, 11 cases of tree-in-bud signs, 6 cases of mucous embolism, 8 cases of solid mass, 5 cases of ground-glass opacity, 4 cases of pleural thickening, 3 cases of pleural effusion, and 2 cases of atelectasis. ConclusionsFor asthma and cystic fibrosis patients, central bronchiectasis on chest CT indicates the diagnosis of ABPA, but it cannot be considered as a characteristic feature. Bronchiectasis combined with high attenuation mucus may be a characteristic feature of ABPA although it is rare.
ObjectiveTo investigate the clinical features and relationship of anthracosis and bronchial anthracofibrosis (BAF).MethodsA retrospective study among 591 patients who did bronchoscopy in this hospital from January 2016 to December 2018 was performed. Of them, 71 patients had anthracosis, including 39 BAF. Their clinical data, bronchoscopic results, CT scan and pulmonary function tests were analyzed and compared.ResultsThe prevalence of anthracosis was 12.0% (71/591), while 54.9% (39/71) of anthrocosis were BAF. BAF patients shared features of old age (77.0±10.4), female domination (59.0%), low smoking ratio (25.6%) and high prevalence of tuberculosis (41.0%). Upper lobe bronchi and right lobe bronchus were the predominant sites of involvement. Right lobe bronchus was the most common site of stenosis or occlusion in BAF. According to CT scan, 69.0% of all anthrocasis cases had enlarged or calcificated lymph node in mediastinal or hilar positions. Paratracheal, parahilar, subcarinal lymph nodes were most frequently involved. Compared BAF with non-BAF patients, BAF patients had significantly more cough and expectoration. There was no statistical differences in age, sex, smoking history, infection with tuberculosis, the distribution of anthracosis and abnormal lymph nodes. Though only 26 of 71 patients performed respiratory function tests, there were significantly more cases of obstructive ventilation function disturbance in BAF than in non-BAF patients.ConclusionsAnthracosis occurs at regular locations in lung, usually accompanied with abnormal mediastinal/hilar lymph nodes and associated with tuberculosis. BAF might be a more severe type of anthracosis.