Objective To explore the way and therapeutic effect of one stage total hi p replacement (THR) intreating ischemic necrosis of femoral head combined with intertrochanteric fracture. Methods From July 1997 to September 2005, one stage THR was performed in 18 cases (11 left and 7 right) of ischemic necrosis of femoral head combined with fresh intertrochanteric fracture, including 13 males and 5 females, with an age range of 32-60 years. There were 11 primary cases, 2 cases of ankylosing spondyl itis, 2 cases of rheumatic arthritis, 2 cases of congenital acetabular dysplasia and 1 case of femoral neck fracture fixed using cannulated cancellous screws postoperatively in all cases of ischemic necrosis of femoral head. They suffered from ischemic necrosis of femoral head for 8 years (4-23 years). According to Evan’s intertrochanteric fracture classification, there were 4 cases of type II, 6 cases of type III, 5 cases of type IV and 3 cases of type V. According to the Ficat ischemic necrosis of femoral head classification, there were 5 cases of type III, and 13 cases of type IV. The disease course was 2-12 hours. The average value of Harris evaluation was 35.2 preoperatively. The prosthesis of biology was used. Results All wounds healed by first intention. One case suffered deep venous thrombosis 3 days postoperatively and recovered completely after treatment. No infection of urinary system and lung as well as no bedsore occurred postoperatively. The X-ray films showed that the fracture ends healed and that prosthesis had good form attitude and position after 4 months of operation. All cases were followed up for 2 years. They could walk and take care of themselves after 6 months. The average value of Harris evaluation was 94.7 points postoperatively (P lt; 0.05). The results were excellent in 15 cases, good in 2 cases, fair in 1 case according to Harris evaluation standard of THR; the excellent and good rate was 94.4%. Conclusion One stage THR for treating ischemic necrosis of femoral head combined with intertrochanteric fracture can avoid secondary operation. It could resume the ideal function of the hip joint.
Objective To explore the treatment of dislocation after total hip replacement. Methods From July 1997 to October 2004, 23 casesof dislocation after total hip replacement were treated,including 9 males and 14 females and aging 5379 years. The CT and serial X-ray films were taken to observe the position of prostheses. The strength of their hip abductor was also tested. In the patients without loosening, closed reduction was attempted at first. The stability of hip was tested. If closed reduction failed, the offset or/and parts of the components was adjusted, then the capsular was repaired. If instabilitystill existed, revision was adopted. Results In 23 cases of dislocation, 10 cases were treated successfully by closed reduction. In 12 patients who failed reduction, 5 were given open reduction combined with capsular repairing; the offset was adjusted by lengthening femoral head in 2 cases; rim liners were elevated in 2 cases; and larger offset was used and abnormal liner was adjusted in 1 case. Revision was used in 1 case having loosening and 2 cases having instability. Allpatients were followed up 1 year to 5 years (1.9 years on average). The Harrisscoring was 7294 (87 on average). Conclusion The treatment of dislocation after total hip replacement should use different ways according to the causes of dislocation and the stability of hip.
Objective To observe expression of Caspase-3 and apoptosis around the prosthesis and explore the relationship of the expression and the apoptosis with the periimplant osteolysis. Methods From April 2001 to August 2006, 16 patients (10 males, 6 females) underwent the revision total hip arthroplasty surgery, who had the primary total hip arthroplasty at the ages of 45-67 years and had the revision total hip arthroplasty at the ages of 55-78 years, with the implantation duration of 7-13 years. According to their preoperative X-ray films andthe findings during the operation, the patients were divided into two groups: theloose/osteolytic group (n=8) and the loose/non-osteolytic group (n=8). The interface tissues were obtained from the peri-implant region in the patients. The synovial samples were taken from another 6 patients (2 males, 4 females; age, 54-68years; illness course, 9-15 years), who underwent the primary total hip arthroplasty for osteoarthritis. These 6 patients were used as controls. The tissues were prepared for the immunohistochemical assays to determine the expression of Caspase-3. The TUNEL assays were performed to quantify the apoptotic cells. The quantitative analysis on the positive cells and the correlation with the presence of the particulate wear debris and the severity of osteolysis were also performed. Results The level of the expression for Caspase-3 and the apoptosis index inthe loose/osteolytic group were significantly increased when compared with those in the loose/non-osteolytic group and the control group (P＜0.01). The polyethylene particles were surrounded by more positive cells than the metal particles. The positive cells were present at a higher level in the tissue sections where the high-wear status was present when compared with the areas where the low-wear status was present (P＜0.05). Conclusion There is a statistical correlation of the Caspase-3 expression to the apoptosis index and to the presence of the particulate wear debris and the severity of osteolysis, which may be one of the key points for the bone reconstruction inhibition and the bone resorption at the boneimplant interface under the stimulation of the wear debris. The apoptosis is involved in the pathogenesis of the aseptic loosening, which is closely related to the signal transportation of Caspase-3.
ObjectiveTo investigate the effect of preoperative smoking intervention on the incidence of postoperative complication in patients undergoing total hip replacement. MethodsPatients undergoing elective total hip replacement were randomly (block randomization) assigned to either smoking intervention group or control group 4 weeks before scheduled hip replacement. Smoking intervention group received counseling and nicotine replacement therapy and achieved smoking cessation or at least 50% smoking reduction while the control group received standard care with little or no information about the risk of smoking or smoking cessation counselling. Anesthesia was done in accordance with the practice of our hospital with either general anesthesia or combined spinal-epidural anesthesia (CSEA). An assessor who was masked to the intervention recorded the incidence of cardiopulmonary, renal, neurological, or surgical complications and duration of hospital admittance and treatment in intensive care unit (ICU) of two groups of patients. ResultsA total of 120 patients were finally included (60 cases were in each group, all male, ASAⅠ-Ⅲ, aged 65-82 years, weighting 42-75 kg). A total of 56 patients in the smoking intervention group and 57 in the control group were analyzed finally. The results showed that, the smoking intervention group was lower than the control group in the incidences of post-operative complications (12/56 vs. 39/57, P=0.000), postoperative wound-related complications (3/56 vs. 21/57, P=0.000), incision infection (1/56 vs. 13/57, P=0.001), and the requirement of secondary surgery (1/56 vs. 9/57, P=0.022) and wound debridement (1/56 vs. 8/57, P=0.040). The median length of stay in the smoking intervention group was significantly less than that of the control group (14 days vs. 26 days, P=0.000). ConclusionAn effective smoking intervention 4 weeks before surgery reduces incidence of postoperative complications.
Objective To investigate and explore the clinical effect of preoperative exercise intervention on total hip arthroplasty. Methods Seventy-three patients who underwent primary unilateral total hip replacement (THR) in the Orthopedics Department, the Second Hospital of Jilin University between March 2017 and January 2018 were divided into 2 groups: treatment group (n=37) and control group (n=36). Patients in treatment group received exercise intervention and routine education since 4 weeks before surgery; the control group just received routine education before surgery and both groups underwent the same routine rehabilitation training. The Visual Analogue Scale (VAS) was evaluated and compared separately between the two groups at 4 weeks before surgery (T0), 1 day before surgery (T1), before discharge (T2), 1 month after discharge (T3), and 3 months after discharge (T4). The results of Hip Harris score and Time Up and Go test (TUG) were evaluated and compared separately between the two groups at T0, T1, T3 and T4. Results Time of TUG of the treatment group and the control group at T1, T3 and T4 were (14.59±3.15) vs. (16.31±3.31) s, (13.61±2.76)vs. (15.25±3.08) s, (12.49±2.37)vs. (14.22±2.65) s, respectively, and the differences between the two groups at T1, T3 and T4 were all statistically significant (P<0.05). In terms of VAS and Harris scores, both groups showed significant improvement after surgery at different time nodes (P<0.05), but the differences between the two groups was not statistically significant (P>0.05). Conclusion Preoperative exercise intervention can effectively improve the walking ability of THR patients and reduce the risk of falls after discharge, but it did not reduce postoperative pain or improve postoperative hip Harris score after discharge.