Objective To review the recent research progress of base and clinical application of tracheal replacement. Methods Literature concerning tracheal prosthesis and the current achievements were extensively and comprehensively reviewed. Results Most tracheal lesions can be resected and achieve primary reconstruction, but the resectable length was limited.Tracheal replacement was an efficient and feasible way to substitutethe defects resulting from extended resection. Conclusion Newtechniques such as tissue engineering, tracheal transplantation, new tracheal prosthesis of biomaterials break fresh ground for the more rapid development of tracheal surgery.
Objective To study the research advance in tracheal allografts undergoing revascularization and reepithelialization. Methods Therecent literature concerned was reviewed. The tracheal allografts are embedded in the omentum, which they were revascularized and reepithelialized by planting in self-epithelia, then the allografts with their omental pedicles were transplanted orthotopically to the cervical or the thoracic portion of the trachea. Results Compared withthe onestage tracheal allograft approach using the greater omentum, the twostage approach could increase the successful rate of revascularization and reepithelialization, and made the allografts accord with their physiology. Conclusion If the approach is successful, it can reduce graft-rejection, prevent graft-collapse and increase graft-viability after tracheal allograft.