【摘要】 目的 总结应用Hyper-CVAD/MA强力化疗方案治疗成人急性淋巴细胞白血病的护理措施，以提高护士对相关患者的护理水平。 方法 2004年6月-2009年2月，应用Hyper-CVAD/MA强力化疗方案治疗80例急性淋巴细胞白血病患者，在化疗过程中，护士密切监护并观察化疗药物的不良反应，积极给予护理措施。 结果 80例急性淋巴细胞白血病患者均顺利完成化疗并出院，未发生与护理相关的不良反应。 结论 应用Hyper-CVAD/MA强力方案治疗成人急性淋巴细胞白血病，护理工作十分重要。严密观察病情，强化化疗护理，可以有效地预防和减轻毒副反应的发生。【Abstract】 Objective To summarize the nursing measures of patients with adult acute lymphocytic leukemia treated with hyper-CVAD/MA chemotherapy regimen, a dose-intensive regimen, and improve the level of nursing care. Methods Eighty patients with acute lymphocytic leukemia treated by hyper-CVAD/MA regimen in this hospital were included June 2004 to February 2009.The patients were closely monitored and given nursing interventions.The drug adverse reactions were observed. Results All patients completed scheduled regimen and discharged successfully without any adverse events associated with nursing care. Conclusion The nursing interventions are very important for the patients with adult acute lymphocytic leukemia treated with hyper-CVAD/MA regimen, and close observation on the patients and strengthening nursing care can effectively prevent and mitigate the occurrence of toxicity.