ObjectiveTo study the brain tissue oxygen and prognosis index of the postoperative patients with hypertensive intracerebral hemorrhage (HICH) associated with secondary brain insults. MethodsA total of 120 patients with HICH from January 2006 to June 2013 were treated by neurosurgical intervention. Postoperative monitoring of factors affecting the secondary brain insults in the 120 patients and of brain tissue oxygen in 10 patients was performed and statistically analysis was carried out. ResultsSecondary brain insults had a significant influence on the prognosis of postoperative patients with hypertensive intracerebral hemorrhage, and was correlated with brain tissue oxygen metabolism. ConclusionAbnormal secondary brain insults affect brain tissue oxygen metabolism, which may further deteriorate the brain damage and can lead to poor prognosis.