ObjectiveTo study the effect of octreotide on acute adhesive intestinal obstruction． MethodsFifty-two patients with adhesive intestinal obstruction from January 2009 to January 2011 in this hospital were divided into octreotide treatment group (n=28) and routine treatment group (n=24) according to the treatment methods. Apart from routine treatments, octreotide was administrated in the octreotide treatment group while traditional treatment in the routine treatment group．The effectiveness was observed and compared between two groups. ResultsThe cure rate of the octreotide treatment group was significantly higher than that of the routine treatment group (Plt;0.05). The anus exhausting and defecating time was earlier, hospitalization time was shorter, and gastrointestinal decompression of the treatment octreotide group as compared with the routine treatment group (Plt;0.05)． ConclusionConventional therapy combining with intravenous infusion of octreotide in patients with acute adhesive intestinal obstruction can improve the clinical symptoms and success rate of treatment．