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find Author "XU Pingrong" 4 results
  • Shenfu Injection for Heart Failure in Old Patients: A Meta-analysis

    目的 评价参附注射液治疗老年人心力衰竭疗效和安全性。 方法 计算机检索Cochrane图书馆,Medline(1950年-2013年10月),Embase(1980年-2013年10月),中国知网(1979年1月-2013年10月)、万方(1986年1月-2013年10月)、维普(1989年1月-2013年10月)数据库,全面收集参附注射液联用西药常规治疗(试验组)与西药常规治疗疗效(对照组)比较的随机对照试验(RCT),分别由2名研究者根据纳入与排除标准,独立筛选文献、提取资料并评价文献质量,采用Revman 5.1软件进行Meta分析。 结果 共纳入8个研究559例患者,研究质量均为C级。Meta分析结果显示:与对照组比较,试验组临床疗效明显提高、症状改善[RR=1.20,95%CI(1.11,1.29),P<0.000 01],左室舒张末期内径减小明显[MD=5.90,95%CI(3.97,7.84),P<0.000 01]、6 min步行试验距离增加[MD=62.48,95%CI(43.12,81.84),P<0.000 01],但左室射血分数两组差异无统计学意义[MD=4.79,95%CI(-0.07,9.65),P=0.05]。 结论 参附注射液与西药常规治疗联用能进一步提高老年心力衰竭患者的临床疗效,且安全性较好。

    Release date:2016-08-26 02:09 Export PDF Favorites Scan
  • Efficacy and Safety of Different Doses of Intravenous Immunoglobulin in the Treatment of Relapsing-Remitting Multiple Sclerosis: A Systematic Review

    Objective To evaluate the efficacy and safety of different doses of intravenous immunoglobulin (IVIG) in the treatment of relapsing-remitting multiple sclerosis (RRMS). Methods We searched for randomized controlled trials of different doses of IVIG in the treatment of RRMS. We screened the retrieved studies according to the predefined inclusion and exclusion criteria, evaluated the quality of included studies, and performed meta-analyses with The Cochrane Collaboration’s Revman 4.2.0 software. Results Three randomized controlled trials of different dose of IVIG in the treatment of RRMS were included. One was of high quality and the other two were of lower quality. Heterogeneity was identified in one study which reported IVIG in postpartum RRMS. Two studies reported the relapsefree rate and no significant difference was noted between IVIG and placebo. Two studies reported the annual relapse rate, and no significant difference was observed (OR -0.00, 95% CI -0.36 to 0.36, P=0.98). Two studies reported the MRI lesions, and no difference was identified, either. The incidence of adverse events was similar between IVIG and placebo. Conclusion  There is insufficient evidence to support the dose-effect relationship of IVIG in the treatment of RRMS. Therefore, an individualized dosing regimen should be applied according to patients’ tolerance and economic status.

    Release date:2016-09-07 02:11 Export PDF Favorites Scan
  • Analysis of Narcotics Analgesics Application from 2008 to 2010

    目的 分析四川大学华西医院麻醉性镇痛药应用的现状及趋势,并行客观评价。 方法 对2008年-2010年四川大学华西医院麻醉性镇痛药品的种类、用量、金额、用药频度等进行归类统计、比较和分析。 结果 住院部使用麻醉药品的用量及金额呈上升趋势。临床应用以芬太尼类居首。新型麻醉药品的应用也有上升趋势。 结论 麻醉性镇痛药的应用基本合理,但创建无痛医院仍需进一步完善,并提交合理用药水平。

    Release date:2016-09-08 09:13 Export PDF Favorites Scan
  • Analysis on the Application of Cyclooxygenase-2 Inhibition Drugs

    目的 研究环氧合酶-2抑制剂药物的应用状况和发展趋势,为临床合理、有效、经济地选用药物提供科学依据。 方法 采用金额排序和用药频度(DDDs)、日均费用(DDC)方法,对四川大学华西医院2008年-2010年环氧合酶-2抑制剂药物的临床应用情况进行统计分析。 结果 2008年-2010年间,该院环氧合酶-2抑制剂药物的应用数量和销售金额呈逐年上升趋势,其中选择性环氧合酶-2抑制剂药物的用量增幅较大,非选择性环氧合酶-2抑制剂药物用量呈下降趋势。 结论 该院环氧合酶-2抑制剂药物临床应用合理,选择性环氧合酶-2占主导地位,有较好的发展前景。

    Release date:2016-09-08 09:16 Export PDF Favorites Scan
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