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find Author "YAN Chenglei" 1 results
  • Clinical Characteristics of Young Patients with Stanford Type A Aortic Dissection

    Abstract: Objective To summarize the clinical characteristics of young patients with Stanford type A aortic dissection. Methods We retrospectively analyzed 54 patients with Stanford type A aortic dissection who received surgical treatment in General Hospital of PLA between March 2004 and June 2011. All the patients were divided into two groups: a young patient group with patients’ age less than 40 years and a control group with patients’ age more than or equal to 40 years. There were 23 patients including 17 males and 6 females with an average age of 34.2±6.3 years in the young patient group and 31 patients including 27 males and 4 females with an average age of 51.5±6.8 years in the control group. The clinical characteristics and surgical treatment outcomes of the two groups were compared. Results There was no statistical difference in cardiopulmonary bypass(CBP)time(224.4±83.1 min vs. 215.0±88.0 min, t=0.39, P=0.69) and aortic cross-clamping time(152.3±60.8 min vs. 130.9±51.2 min, t=1.34, P=0.18)between the two groups. Compared with the patients in the control group, young patients were more likely to have congenital malformations with rate at 34.7%(8/23) vs. 6.4%(2/31) with χ2=5.27, P=0.02, such as Marfan syndrome and bicuspid aortic valve. The mortality of the young patients was similar to patients in the control group at rate of 13.0%(3/23)vs.12.9%(4/31) with χ2=0.15 and P=0.69, but postoperative mental and neurological complications rate in the young patient group were less frequent than those in the control group at 4.3%(1/23)vs. 32.2%(10/31) with χ2=5.32 and P=0.02. Conclusion Young patients with Stanford type A aortic dissection have fewer cardiovascular risk factors for aortic dissection but are more likely to have congenital malformations. The surgical methods are more active for young patients with less frequency of postoperative mental and neurological complications.

    Release date:2016-08-30 05:50 Export PDF Favorites Scan
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