Objective To investigate the adverse pregnant outcomes of hospitalized pregnant women in Lanzhou city, and analyze the corresponding risk factors and provide basis for the further research on better child-bearing and child-rearing. Methods In two provincial-level hospitals and one provincial-level specialized hospital, the method of cluster random sampling was applied to extract 6 825 medical records from January 2004 to December 2005. The relevant information was abstracted and correlative analyses were undertaken. Results The incidence of adverse pregnancy outcomes for the hospitalized pregnant women in Lanzhou city was 14.65%. Single-factor unconditional logistic regression analyses displayed that the variables with statistical significance were the number of previous pregnancies, the number of previous child delivery, abortion history, abnormal gestation history, and past medical history, whereas multi-factor unconditional logistic regression analyses revealed that the adverse pregnancy outcomes were positively correlated with abnormal gestation history and the number of previous pregnancies with statistical significance. Conclusion The incidence of adverse pregnancy outcomes for the hospitalized pregnant women in Lanzhou city is quite high. Abnormal gestation history and the number of previous pregnancies are the main risk factors for the adverse pregnancy outcomes.
Objective To explore the correlation between adverse pregnancy outcomes and previous bearing status. Methods The related information of pregnant and postnatal women was extracted from 6825 hospitalized records in two general hospitals and one special hospital, which were selected by the method of cluster sampling, and the related rate and correlation analyses were calculated. Results Women who had abortion history were much easier to cause adverse pregnancy outcomes compared to those who had no abortion history, with the incidence rates of 16.83% and 13.31%, respectively; the incidence rates of adverse pregnancy outcomes of women who ever had zero, one, and two or more than twice of delivery were 14.14%, 16.34% and 22.78%, respectively; the rates of women on their third or more than third, second, first or zero pregnancy were 49.14%, 18.05%, 14.22% and 12.88%, respectively; and the rates of adverse pregnancy outcomes of women with abnormal and normal gestation history were 31.06% and 14.21%, respectively. Conclusion The previous abortion, delivery times and abnormal gestation history are highly related to adverse pregnancy outcomes. Therefore, in order to reduce adverse pregnancy outcomes, it is necessary to make an effective family planning and decrease abortion and pregnancy.
Objective To study oxygen carrying capacity of red blood cell in children with congenital left-to-right shunt (CLRS) and discuss its clinical significance. Methods A total of 62 children with CLRS were selected as a trial group and 40 healthy children who had accepted clinical physical examination as a control group. ELISA test was applied to determine 2,3 -DPG content of red blood cells. At the same time, pH, PaO2, PaCO2, Hb, P50O2 and relevant outcomes were tested for correlation analysis. Results Red blood cell 2,3-DPG (2.76±0.98 μmol/mL) was higher than that of the control group. PaO2, pH, Hb were lower than those of the control group with significant differences. Among the types of CLRS, 2,3 -DPG of ventricular septal defect was the highest and that of patent ductus arteriosus ranked the second, the two of which had a significant difference (P=0.007). As for red blood cell of children with congenital heart diseases, there was linear correlation between 2,3- DPG and PaO2 as [2,3-DPG=12.007 8– (0.154 7×PaO2)], as well as between P50O2 and 2,3 -DPG as [P50O2=26.303 6+ (1.799 2×2,3-DPG)]. Conclusion Children with congenital left-to-right shunt tend to have low oxygen. Therefore, it is important to detect 2,3-DPG of red blood cell, blood gas analysis, and hemoglobin level change, in order to well understand the mechanism of congenital heart disease as well as to guide clinical practice.