ObjectiveTo investigate risk factors of in-hospital death of patient after heart valve replacement (HVR) in Xinjiang. MethodsWe retrospectively analyzed clinical data of 214 patients undergoing HVR in the First Teaching Hospital of Xinjiang Medical university from January 2011 to Month 2014. There were 96 male and 118 female patients with their age of 49.91±13.27 years. According to their postoperative prognosis, all the patients were divided into a death group (21 patients) and a survival group (193 patients). Risk factors of perioperative death were analyzed. ResultsIn-hospital mortality was 9.81% (21/214). There was statistical difference in preoperative prothrombin time (PT), incidences of left ventricular ejection fraction (LVEF)≤50%, NYHA classⅣ, pulmonary arterial pressure (PAP) > 60 mm Hg, cardiopulmonary bypass time≥2 hours, concomitant coronary artery disease and renal failure between the 2 groups (P < 0.05). Logistic regression analysis showed that shortened preoperative PT, PAP > 60 mm Hg, NYHA classⅣand LVEF≤50% were independently risk factors of in-hospital death after HVR (P < 0.05). ConclusionsIndependent risk factors of in-hospital death of patients after HVR in Xinjiang include shortened preoperative PT, PAP > 60 mm Hg, NYHA classⅣand LVEF≤50%. Heightened caution is needed for patients with above risk factors to receive HVR after correction of those risk factors.
ObjectiveTo comprehend the incidence of and to search for the possible risk factors for neonatal congenital heart disease (CHD) in Mianyang after "5·12" Earthquake. MethodsCHD screening was performed on 5536 neonates born between December 2011 and December 2012 by cardiac auscultation, respiration evaluation, blood oxygen saturation determination and color doppler flow imaging. Case control study was applied to study the diagnosed cases of CHD. ResultsSixty-five cases of CHD were found during the screening, and the incidence was 11.74‰. The most common CHD was ventricular septal defect, followed by atrial septum defect and patent ductusarteriosus. Possible risk factors were listed in order of their risks were as follows:family history of CHD, infection history in the early period of pregnancy, drug and alcohol history during pregnancy, and aged pregnancy and smoking history of the parents. However, earthquake experience history of parents was not correlated with CHD incidence. ConclusionEarthquake experience of parents is not correlated with CHD incidence. Enforcing health education for women before gestation, and avoiding or decreasing risk factors exposure can reduce the risk of CHD. CHD screening for neonates can detect CHD as early as possible, which is helpful for intervention during the follow-up, reduction of fatality, and improvement of neonates' quality of life.